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  • Tel: 858.663.9055
  • Email: info@nsjbio.com
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Signal Transduction Antibodies

Home >> Antibodies >> Signal Transduction Antibodies

Signal Transduction Antibodies

NSJ Bioreagents offers the following antibodies in the area of Signal Transduction:
Found all antibodies, displaying 11041 to 11050
DSG1 Antibody / Desmoglein 1 (clone MSVA-544M)
Catalog No : V6068
Applications : IHC
Reactivity : Human
Format : Purified
Recmousemono
DSG1 Antibody for IHC Tissue Microarray (TMA). Immunohistochemistry analysis of Desmoglein 1 DSG1 in formalin-fixed paraffin-embedded human normal and cancer tissue microarrays using recombinant mouse monoclonal antibody clone MSVA-544M. Tissue microarray (TMA) staining with HRP-DAB brown chromogen demonstrates strong membranous localization in stratified squamous epithelium, including skin, esophagus, and tonsil surface epithelium, consistent with suprabasal keratinocyte expression, while most non-stratified epithelia and non-epithelial tissues remain largely negative. Within tumor tissue microarrays, membranous staining is observed in squamous cell carcinomas of the larynx, oral cavity, vulva, and cervix, as well as in selected urothelial carcinomas, reflecting retained epithelial differentiation, whereas most adenocarcinomas and non-epithelial malignancies show minimal to no staining. Evaluation across large TMA panels enables direct comparison of DSG1 expression across diverse tissue types under standardized conditions. The observed staining patterns align with reported Desmoglein 1 expression profiles in the Human Protein Atlas and support its role in desmosomal cell-cell junctions.
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Desmoglein 3 Antibody / DSG3 (clone MSVA-543M)
Catalog No : V6069
Applications : IHC
Reactivity : Human
Format : Purified
DSG3 Antibody for IHC Tissue Microarray (TMA). Immunohistochemistry analysis of Desmoglein 3 DSG3 in formalin-fixed paraffin-embedded human normal and cancer tissue microarrays using mouse monoclonal antibody clone MSVA-543M. Tissue microarray (TMA) staining with HRP-DAB brown chromogen demonstrates strong membranous localization in stratified squamous epithelia, including skin, esophagus, and mucosal tissues, consistent with desmosomal cell-cell junction distribution, while most non-squamous and non-epithelial tissues remain largely negative. Within tumor tissue microarrays, membranous staining is preserved in squamous cell carcinomas, supporting retained epithelial differentiation, whereas most non-squamous malignancies show minimal to no staining. Evaluation across large TMA panels enables direct comparison of DSG3 expression across diverse tissue types under standardized conditions. The observed staining patterns align with reported Desmoglein 3 expression profiles in the Human Protein Atlas.
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Estrogen Receptor alpha Antibody (clone MSVA-564R)
Catalog No : V6071
Applications : IHC
Reactivity : Human
Format : Purified
Recrabbitmono
Estrogen receptor alpha / ER alpha Antibody for IHC. Immunohistochemistry of Estrogen Receptor antibody for IHC in human tissue microarrays. FFPE human normal and cancer tissues were stained with Estrogen Receptor recombinant rabbit monoclonal antibody clone MSVA-564R. Nuclear staining is observed in hormone-responsive epithelial cells, with strong nuclear positivity in breast epithelium and endometrial glands, including proliferative and secretory endometrium. Placental trophoblastic cells also demonstrate nuclear signal. Most non-hormone-dependent tissues such as skeletal muscle, liver, kidney cortex and medulla, pancreas, thyroid gland, and colon mucosa show little to no nuclear staining. In the cancer tissue gallery, strong nuclear staining is present in subsets of breast carcinoma and endometrioid ovarian carcinoma, while ER negative tumors including colorectal adenocarcinoma, renal cell carcinoma, squamous cell carcinoma of the oral cavity, and prostate adenocarcinoma show absent nuclear labeling. The staining pattern is predominantly nuclear, consistent with Estrogen Receptor alpha localization.
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FABP1 Antibody / Fatty acid-binding protein 1 (clone MSVA-501M)
Catalog No : V6073
Applications : IHC
Reactivity : Human
Format : Purified
Recmousemono
FABP1 Antibody for IHC Tissue Microarray (TMA). Immunohistochemistry analysis of Fatty acid-binding protein 1 FABP1, also known as Liver fatty acid binding protein, in formalin-fixed paraffin-embedded human normal and cancer tissue microarrays using mouse monoclonal antibody clone MSVA-501M. Tissue microarray (TMA) staining with HRP-DAB brown chromogen demonstrates strong cytoplasmic localization in hepatocytes of the liver, with additional staining in small intestinal enterocytes and renal proximal tubular epithelial cells, while most other tissues show minimal to absent staining. Within tumor tissue microarrays, hepatocellular carcinoma demonstrates retained cytoplasmic FABP1 expression, whereas most non-hepatic malignancies show minimal or negative staining. Evaluation across large TMA panels enables direct comparison of FABP1 expression across diverse tissue types under standardized conditions. The observed staining patterns align with reported expression profiles in the Human Protein Atlas and support its use as a marker of hepatocellular and enterocyte differentiation.
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CD23 Antibody / Fc epsilon receptor 2 (clone MSVA-023M)
Catalog No : V6074
Applications : IHC
Reactivity : Human
Format : Purified
Recmousemono
CD23 Antibody for IHC Tissue Microarray (TMA). Immunohistochemistry analysis of CD23 molecule FCER2 in formalin-fixed paraffin-embedded human normal and cancer tissue microarrays using mouse monoclonal antibody clone MSVA-023M. Tissue microarray (TMA) staining with HRP-DAB brown chromogen demonstrates strong membranous localization in B lymphocytes within tonsil and lymph node germinal centers, consistent with expression in mature follicular B cells, while most non-lymphoid tissues show minimal to absent staining with only scattered positive lymphoid cells. Within tumor tissue microarrays, distinct membranous staining is observed in CD23-positive B cell lymphomas, whereas the majority of non-lymphoid malignancies remain negative. Evaluation across large TMA panels enables direct comparison of FCER2 expression across diverse tissue types under standardized conditions. The observed staining patterns align with reported CD23 expression profiles in the Human Protein Atlas and support its use as a marker of mature B cell lineage.
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PD-L1 Antibody / B7-H1 / CD274 (clone MSVA-711R)
Catalog No : V6082
Applications : IHC
Reactivity : Human
Format : Purified
Recrabbitmono
PD-L1 Antibody for IHC Tissue Microarray (TMA). Immunohistochemistry analysis of Programmed death-ligand 1 / CD274, also known as PD-L1, in formalin-fixed paraffin-embedded human normal and cancer tissue microarrays using rabbit monoclonal antibody clone MSVA-711R. Tissue microarray (TMA) staining with HRP-DAB brown chromogen demonstrates membranous and cytoplasmic localization consistent with immune checkpoint ligand expression, with minimal to absent staining in most normal tissues and detectable signal in immune cell populations within lymphoid-rich tissues. Within tumor tissue microarrays, variable membranous staining is observed across multiple carcinoma types, reflecting tumor-associated PD-L1 expression and immune evasion mechanisms. Evaluation across large TMA panels enables direct comparison of CD274 expression across diverse tissue types under standardized conditions. The observed staining patterns align with reported PD-L1 expression profiles in the Human Protein Atlas and support its role in immune checkpoint signaling and tumor-immune interactions.
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PSA Antibody / Prostate Specific Antigen / KLK3 (clone MSVA-603R)
Catalog No : V6089
Applications : IHC
Reactivity : Human
Format : Purified
Recrabbitmono
PSA Antibody for IHC. Immunohistochemistry analysis of human tissue microarrays. PSA Antibody for IHC (clone MSVA-603R) was evaluated on formalin-fixed paraffin-embedded human tissue microarrays containing a broad panel of normal tissues and cancers. HRP-DAB staining highlights strong cytoplasmic and luminal signal in prostate epithelial cells of normal prostate tissue, while most other normal tissues show little to no staining. In cancer tissue arrays, strong PSA expression is observed in prostate adenocarcinoma, whereas non-prostatic tumors are largely negative. These staining patterns are consistent with the known tissue specificity of Prostate specific antigen (KLK3) and align with expression profiles reported in the Human Protein Atlas.
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Androgen Receptor Antibody (clone MSVA-367R)
Catalog No : V6092
Applications : IHC
Reactivity : Human
Format : Purified
Recrabbitmono
Androgen Receptor Antibody for IHC. Clone MSVA-367R demonstrates nuclear androgen receptor staining in immunohistochemistry analysis of formalin-fixed, paraffin-embedded human tissue microarrays. In normal tissues, strong nuclear HRP-DAB staining is observed in androgen-responsive cells such as prostate epithelium and seminal vesicle epithelium, with weaker or absent staining in most non-androgen-dependent tissues. Across the cancer tissue microarray, prominent nuclear staining highlights androgen receptor-positive tumors including prostate adenocarcinoma, while many other carcinoma types show little or no detectable signal. The nuclear staining pattern reflects the transcription factor localization of androgen receptor (AR) and clearly delineates AR-positive tumor cell populations within tissue architecture. These immunohistochemistry staining patterns across normal and cancer tissues correspond with androgen receptor expression profiles reported in Human Protein Atlas datasets.
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NCAM / CD56 Antibody (clone MSVA-056R)
Catalog No : V6100
Applications : IHC
Reactivity : Human
Format : Purified
Recrabbitmono
CD56 Antibody for IHC. Immunohistochemistry analysis of an FFPE human tissue microarray (TMA) demonstrates the distribution of CD56 (Neural cell adhesion molecule 1, NCAM1) across a wide range of normal and cancer tissues. Brown chromogenic staining highlights CD56-positive cells with membranous and cytoplasmic signal patterns consistent with the expression of this cell surface adhesion molecule. Strong staining is observed in tissues known to express NCAM1, including neural structures and subsets of immune and neuroendocrine cells, while many epithelial tissues show minimal or absent staining. The staining patterns observed across these tissue microarrays are consistent with the expression profiles reported in the Human Protein Atlas, supporting the expected tissue distribution of CD56.
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Progesterone Receptor Antibody (clone MSVA-570R)
Catalog No : V6103
Applications : IHC
Reactivity : Human
Format : Purified
Recrabbitmono
Progesterone Receptor Antibody for IHC analysis of Progesterone receptor / PGR in human tissue microarrays. FFPE human normal and cancer tissue microarray panels were stained with Progesterone Receptor Antibody for IHC (clone MSVA-570R). Immunohistochemistry demonstrates nuclear HRP-DAB brown staining in hormone-responsive epithelial cells, particularly in breast and uterine tissues, consistent with the known nuclear localization of Progesterone receptor. PR immunohistochemistry staining is widely used in breast cancer evaluation to assess progesterone receptor expression in tumor epithelial cells. Staining patterns observed across normal and cancer tissues are consistent with reported expression profiles, including data from the Human Protein Atlas.
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