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  • Tel: 858.663.9055
  • Email: info@nsjbio.com
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Signal Transduction Antibodies

Home >> Antibodies >> Signal Transduction Antibodies

Signal Transduction Antibodies

NSJ Bioreagents offers the following antibodies in the area of Signal Transduction:
Found all antibodies, displaying 10991 to 11000
KRT19 Antibody for IHC / Cytokeratin 19 (clone MSVA-119M)
Catalog No : V5935
Applications : IHC
Reactivity : Human
Format : Purified
Recmousemono
KRT19 Antibody for IHC Tissue Microarray (TMA). Immunohistochemistry analysis of Keratin 19 KRT19, also known as Cytokeratin 19, in formalin-fixed paraffin-embedded human normal and cancer tissue microarrays using recombinant mouse monoclonal KRT19 antibody clone MSVA-119M. Tissue microarray (TMA) staining with HRP-DAB brown chromogen demonstrates strong cytoplasmic localization in simple and glandular epithelial compartments, including gastrointestinal mucosa, pancreatic and bile ducts, renal tubular epithelium, bronchial epithelium, endometrial glands, prostatic epithelium, and urothelium, while stratified squamous epithelia show limited staining and mesenchymal tissues remain largely negative. Within tumor tissue microarrays, strong positivity is observed in carcinomas with glandular or ductal differentiation, while non-epithelial malignancies show minimal staining. Evaluation across large TMA panels enables direct comparison of KRT19 expression across diverse tissue types under standardized conditions. The observed staining patterns support its role as an epithelial lineage marker and align with reported KRT19 expression profiles in publicly available datasets including the Human Protein Atlas.
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Laminin gamma 1 Antibody / LAMC1 (clone LAMC1/13970R)
Catalog No : V5936
Applications : IHC
Reactivity : Human
Format : Purified
SDS-PAGE Analysis of purified recombinant Basement membrane laminin antibody (clone LAMC1/13970R). Confirmation of Purity and Integrity of Antibody.
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EPCAM Antibody for IHC / Epithelial cell adhesion molecule (clone MSVA-326R)
Catalog No : V5938
Applications : IHC
Reactivity : Human
Format : Purified
Recrabbitmono
EpCAM Antibody for IHC Tissue Microarray (TMA). Immunohistochemistry analysis of Epithelial cell adhesion molecule EPCAM, also known as CD326, in formalin-fixed paraffin-embedded human normal and cancer tissue microarrays using recombinant rabbit monoclonal EpCAM antibody clone MSVA-326R. Tissue microarray (TMA) staining with HRP-DAB brown chromogen demonstrates strong membranous localization in epithelial structures, including colon mucosa, small intestine, stomach, prostate, and endometrial glands, while non-epithelial tissues such as skeletal muscle, lymphoid tissues, and stromal compartments show minimal to absent staining. Within tumor tissue microarrays, robust membranous positivity is observed across multiple epithelial malignancies including colorectal adenocarcinoma, breast carcinoma, lung adenocarcinoma, ovarian carcinoma, pancreatic carcinoma, and urothelial carcinoma, while mesenchymal tumors and non-epithelial malignancies remain largely negative. Evaluation across large TMA panels enables direct comparison of EPCAM expression across diverse tissue types under standardized conditions. The observed staining patterns align with reported EPCAM expression profiles in the Human Protein Atlas and support its use in identifying epithelial-derived tumor cells.
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MCM4 Antibody / Minichromosome maintenance complex component 4 (clone MCM4/3041)
Catalog No : V5941
Applications : IHC, WB
Reactivity : Human
Format : Purified
Immunohistochemistry staining of formalin-fixed, paraffin-embedded human colon with MCM4/DNA replication licensing factor 4 antibody (clone MCM4/3041). Strong nuclear brown staining is observed in proliferating epithelial cells lining the colonic glands, consistent with MCM4 as a replication licensing factor and proliferation-associated marker, while surrounding stromal cells show minimal to weak labeling. Heat-induced epitope retrieval was performed by boiling tissue sections in pH 9, 10mM Tris with 1mM EDTA for 20 min followed by cooling prior to staining.
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MCM4 Antibody / DNA replication licensing factor MCM4 (clone MCM4/13209R)
Catalog No : V5942
Applications : IHC, WB
Reactivity : Human
Format : Purified
Recrabbitmono
Western blot analysis of A431 cell lysate using recombinant MCM4/Cell proliferation marker MCM4 antibody (clone MCM4/13209R). A prominent band is detected at approximately 100 kDa, corresponding to the predicted molecular weight of MCM4, with a characteristic doublet pattern consistent with different phosphorylation states of this cell cycle–regulated protein.
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MCM5 Antibody / Minichromosome maintenance complex component 5 (clone MCM5/3200)
Catalog No : V5943
Applications : IHC, WB
Reactivity : Human
Format : Purified
Microvalidated
Western Blot analysis of human Ramos cell lysate using MCM5/MCM complex protein 5 antibody (clone MCM5/3200). Expected molecular weight: 80~90 kDa.
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MCM5 Antibody / DNA replication licensing factor MCM5 (clone rMCM5/13646)
Catalog No : V5944
Applications : IHC, WB
Reactivity : Human
Format : Purified
Recmousemono
IHC analysis of formalin-fixed, paraffin-embedded human colon tissue using recombinant Minichromosome maintenance protein 5/MCM5 antibody (recombinant mouse monoclonal clone rMCM5/13646). Strong nuclear brown chromogenic staining is observed in proliferating colonic epithelial cells, consistent with nuclear localization of Minichromosome maintenance protein 5, while surrounding non-proliferative cells show reduced staining. Inset: PBS used in place of primary antibody as secondary-only negative control. Heat-induced epitope retrieval was performed by boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 minutes at 95oC followed by cooling at room temperature for 20 minutes.
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MCM5 Antibody / Replication licensing factor MCM5 (clone MCM5/13320R)
Catalog No : V5945
Applications : IHC, Knockdown, WB
Reactivity : Human
Format : Purified
Recrabbitmono
Immunohistochemistry of recombinant MCM complex component 5 antibody in formalin-fixed, paraffin-embedded human tonsil. Strong nuclear brown staining is observed in proliferating lymphoid cells within germinal centers, consistent with MCM5 expression in actively cycling cells, while surrounding non-proliferating cells show weaker or absent staining. Inset: PBS used in place of primary antibody as a negative control shows no specific staining. Heat-induced epitope retrieval was performed by boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 minutes at 95oC followed by cooling at room temperature.
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MMP9 Antibody / Matrix metalloproteinase 9 (clone r15W2)
Catalog No : V5949
Applications : IHC
Reactivity : Human
Format : Purified
Recmousemono
Immunohistochemistry analysis of Gelatinase B / MMP9 antibody (clone r15W2) in human spleen tissue. Formalin-fixed, paraffin-embedded human spleen section shows cytoplasmic brown chromogenic staining in scattered immune cells within the splenic parenchyma, consistent with MMP9 expression, while surrounding lymphoid cells display minimal staining and nuclei appear blue. The inset shows PBS used in place of primary antibody as a negative control with no specific staining observed. Heat-induced epitope retrieval was performed by heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95oC followed by cooling at room temperature for 20 minutes prior to staining.
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MUC4 Antibody / Mucin 4 (clone MUC4/2863)
Catalog No : V5951
Applications : IHC
Reactivity : Human
Format : Purified
Analysis of Protein Array containing more than 19,000 full-length human proteins using ASGP-2/MUC4 antibody (clone MUC4/2863). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
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