NSJ Bioreagents

KRT10, also known as keratin 10, cytokeratin 10 and CK10, is a type I cytokeratin protein found in the skin's epidermis. This protein is a crucial component of the intermediate filaments that provide structural support to our skin cells. KRT10 plays a vital role in the formation of the skin's barrier, which protects us from environmental aggressors such as UV radiation, pollution, and pathogens. Healthy levels of KRT10 are essential for maintaining the integrity of the skin barrier. When the levels of KRT10 are disrupted, it can lead to various skin conditions, such as epidermolytic hyperkeratosis and ichthyosis. These conditions result in thickened, scaly skin that is prone to cracking and infections.

Keratin 10 (KRT10) is an essential protein that plays a crucial role in maintaining the structural integrity of the skin. As such, the study of the KRT10 protein has garnered significant interest in the field of dermatology and cell biology. One powerful tool that is often used in the study of KRT10 is the KRT10 antibody with techniques such as ELISA, immunohistochemistry, flow cytometry, western blot, and immunofluorescence. These techniques allow researchers to visualize and study the distribution and expression of KRT10 in various tissues and cell types.

Immunohistochemistry is a widely used technique that allows for the visualization of proteins in tissue samples. The use of the KRT10 antibody in immunohistochemistry can provide valuable insights into the expression patterns of KRT10 in different types of human tissues, such as skin, hair, and nails.

Flow cytometry is another powerful technique that can be used to analyze the expression of KRT10 at the single-cell level. By using the KRT10 antibody in flow cytometry experiments, researchers can identify and sort cell populations based on their KRT10 expression levels, allowing for a more in-depth analysis of KRT10 function.

Western blotting is a technique that is commonly used to detect and quantify proteins in cell lysates. By using the KRT10 antibody in western blot experiments, researchers can confirm the presence of KRT10 in cell samples and study changes in KRT10 expression under different experimental conditions.

Immunofluorescence is a technique that allows for the visualization of proteins within cells using fluorescently labeled antibodies. By using the KRT10 antibody in immunofluorescence experiments, researchers can study the subcellular localization of KRT10 and examine its interactions with other proteins within the cell.

The KRT10 antibody is a valuable tool for researchers studying the role of KRT10 in skin biology and cell structure. By utilizing techniques such as immunohistochemistry, flow cytometry, western blot, and immunofluorescence, researchers can gain a better understanding of the expression and function of KRT10 in various biological contexts.