NSJ Bioreagents

Cytokeratin proteins are a diverse group of fibrous proteins that are primarily found in epithelial cells, which are the cells that line the surfaces of organs and tissues in the body. They can be idenfied in cell populations and tissue using Cytokeratin antibodies. Ctyokeratin proteins provide structural support to these cells, helping to maintain their shape and integrity. In addition to their role in maintaining cell structure, cytokeratins are also involved in cell signaling and communication, making them essential for the proper functioning of various biological processes. Due to their crucial role in maintaining cell structure and function, cytokeratin proteins are often implicated in the development and progression of various diseases. For example, abnormalities in cytokeratin expression have been linked to certain types of cancer, including breast, lung, and prostate cancer. In these cases, changes in cytokeratin levels can lead to uncontrolled cell growth and proliferation, ultimately leading to the formation of tumors. Furthermore, cytokeratin proteins have also been associated with certain autoimmune diseases, such as rheumatoid arthritis and lupus. In these conditions, the immune system mistakenly targets cytokeratin proteins, leading to inflammation and tissue damage. By understanding the role of cytokeratin proteins in disease, researchers are working towards developing targeted therapies that can help to mitigate the effects of these conditions.

Cytokeratin antibodies are valuable tools for researchers looking to study epithelial cells in various biological samples. One of the most common uses of cytokeratin antibodies is in western blotting, a technique that allows researchers to detect specific proteins in complex biological samples. By using a cytokeratin antibody in a western blot, researchers can accurately identify and quantify cytokeratin proteins in their samples.

In addition to western blotting, cytokeratin antibodies are also commonly used in techniques such as flow cytometry, immunofluorescence, immunohistochemistry, and ELISA. Flow cytometry allows researchers to analyze individual cells based on their protein expression, while immunofluorescence and immunohistochemistry techniques allow for the visualization of cytokeratin proteins in tissue samples. ELISA, on the other hand, is a quantitative technique that can be used to measure the levels of cytokeratin proteins in biological samples.

Cytokeratin antibodies are powerful tools for researchers working in the field of cell biology. By using these antibodies in various techniques such as western blot, flow cytometry, immunofluorescence, immunohistochemistry, and ELISA, researchers can gain valuable insights into the structure and function of epithelial cells.