NSJ Bioreagents

KRT15 antibody is used to study and characterize the expression of KRT15, also called Keratin 15, a type of protein that belongs to the keratin family. Keratins are fibrous proteins that make up the structural components of hair, nails, and skin. KRT15 specifically plays a key role in the formation of hair follicles, which are essential for the growth and maintenance of healthy hair. As a component of hair follicles, KRT15 is essential for maintaining the integrity and strength of hair strands. Without adequate levels of KRT15, hair follicles may become weak and prone to damage, leading to hair loss and breakage. Additionally, Keratin 15 helps to regulate the growth cycle of hair, ensuring that new hair strands are continuously produced to replace old and damaged ones.

Cytokeratin 15 / Keratin 15 / KRT15 is a type I keratin protein that plays a crucial role in maintaining the structural integrity of epithelial tissues. Its expression has been linked to various pathological conditions, making it an important target for research and diagnostics. Using a KRT15 antibody, different laboratory techniques such as immunofluorescence, western blot, immunohistochemistry, and flow cytometry can be used to study the Keratin 15 protein.

Immunofluorescence is a powerful technique that allows researchers to visualize the spatial distribution of proteins within a cell or tissue sample. By using a KRT15 antibody labeled with a fluorescent dye, scientists can specifically target and detect KRT15 expression in various cell types. This technique is particularly useful for studying the localization of KRT15 within different subcellular compartments.

Western blotting is a widely used technique for detecting and quantifying specific proteins in a complex mixture. By using a KRT15 antibody in a western blot assay, researchers can determine the expression level of KRT15 in different samples. This information is crucial for understanding the role of KRT15 in various biological processes and disease states.

Immunohistochemistry is a technique used to visualize the expression of proteins in tissue samples. By using a KRT15 antibody in an immunohistochemistry assay, researchers can determine the localization and abundance of Keratin 15 in different tissues. This information is valuable for understanding the role of KRT15 in the development and progression of diseases such as cancer.

Flow cytometry is a high-throughput technique used to analyze the physical and chemical characteristics of individual cells in a population. By using a KRT15 antibody in a flow cytometry assay, researchers can identify and quantify Keratin 15-positive cells within a heterogeneous cell population. This information is essential for studying the distribution and function of KRT15 in different cell types.

The KRT15 antibody is a valuable tool for researchers studying the role of KRT15 in various biological processes and disease states. By utilizing techniques such as immunofluorescence, western blot, immunohistochemistry, and flow cytometry, scientists can gain valuable insights into the expression and function of Keratin 15 in different cell types and tissues.