KRT15 Antibody / Keratin 15 Antibody

KRT15 Antibody Overview

KRT15 Antibody detects keratin 15, a type I intermediate filament protein expressed in the basal layer of stratified epithelia. KRT15 is particularly enriched in the bulge region of hair follicles, where it serves as a marker of epithelial stem cells. This localization has made KRT15 one of the most widely used markers for identifying skin stem cell populations with regenerative capacity.

In addition to its role in hair follicle biology, KRT15 is expressed in basal keratinocytes of epidermis and other stratified epithelia. Its expression is often downregulated during stress, wound healing, or tumorigenesis, making it a valuable biomarker for both normal and pathological epithelial states. The KRT15 Antibody provides researchers with a reliable tool for studying basal epithelial biology, skin stem cell dynamics, and disease-related changes in keratin expression.

Because of its stem cell associations, Keratin 15 Antibody reagents are indispensable in dermatology, oncology, and regenerative medicine.

Why Choose KRT15 Antibodies from NSJ Bioreagents?

NSJ Bioreagents offers KRT15 Antibodies validated for immunohistochemistry, immunofluorescence, western blotting, ELISA, and flow cytometry. Each KRT15 Antibody is rigorously tested for specificity to keratin 15 and minimal cross-reactivity with related keratins.

By selecting a KRT15 Antibody from NSJ Bioreagents, scientists gain reagents optimized for reproducibility. Our antibodies provide clear staining of basal keratinocytes, consistent detection in lysates, and strong performance across experimental applications. With comprehensive datasheets, suggested positive controls, and validated protocols, NSJ Bioreagents ensures that Keratin 15 Antibody products provide accuracy and confidence in both basic and translational studies.

Applications of KRT15 Antibodies

The KRT15 Antibody has broad applications spanning stem cell biology, dermatology, and oncology.

1) Stem Cell Biology

• KRT15 Antibodies identify epithelial stem cells in the hair follicle bulge.

• The KRT15 Antibody supports studies of stem cell renewal and differentiation.

• Keratin 15 Antibody reagents help evaluate regenerative potential in tissue models.

2) Skin Biology

• KRT15 Antibodies mark basal keratinocytes in stratified epithelia.

• The KRT15 Antibody is used to study epidermal homeostasis and differentiation.

• Keratin 15 Antibody products highlight changes in basal layer organization during stress.

3) Wound Healing and Regeneration

• KRT15 Antibodies clarify how basal keratinocytes respond to injury.

• The KRT15 Antibody is applied to track stem cell activation during repair.

• Keratin 15 Antibody reagents support studies of re-epithelialization.

4) Oncology and Tumor Biology

• KRT15 Antibodies detect altered expression in basal cell carcinomas.

• The KRT15 Antibody helps distinguish tumor subtypes in skin and epithelial cancers.

• Keratin 15 Antibody products provide biomarkers for prognosis and therapeutic evaluation.

5) Hair and Follicle Biology

• KRT15 Antibodies mark the bulge region as a reservoir of stem cells.

• The KRT15 Antibody supports research on hair follicle cycling and regeneration.

• Keratin 15 Antibody reagents are applied in studies of alopecia and follicular disorders.

6) Regenerative Medicine

• KRT15 Antibodies validate stem cell-derived epithelial models.

• The KRT15 Antibody ensures correct basal epithelial identity in tissue-engineered constructs.

7) Translational Medicine and Drug Development

• KRT15 Antibodies are used in preclinical models of skin regeneration.

• The KRT15 Antibody supports biomarker validation in dermatology clinical trials.

• Keratin 15 Antibody reagents are applied in drug testing for wound healing and epithelial repair.

Why Are KRT15 Antibodies Important?

Keratin 15 is a hallmark marker of epithelial stem cells and basal keratinocytes. The KRT15 Antibody provides researchers with a powerful tool for detecting this protein, while Keratin 15 Antibody reagents more broadly support discoveries in skin biology, oncology, and regenerative medicine.

In stem cell biology, KRT15 Antibodies identify progenitor populations essential for epithelial renewal. In dermatology, the KRT15 Antibody highlights basal layer dynamics in health and disease. In oncology, Keratin 15 Antibody tools help classify tumors and uncover mechanisms of malignant transformation.

Clinically, KRT15 is increasingly recognized as a biomarker for regenerative capacity and tumor stratification. By enabling accurate detection, the KRT15 Antibody bridges molecular biology with translational research, supporting both scientific discovery and patient care.

Conclusion

Keratin 15 is a basal epithelial and stem cell marker with critical roles in tissue renewal, disease, and oncology. The KRT15 Antibody equips researchers and clinicians with a precise tool for studying keratin 15 expression, while Keratin 15 Antibody reagents more broadly support progress in regenerative medicine, dermatology, and cancer research. By connecting molecular insights with clinical application, these antibodies remain indispensable for advancing biomedical discovery and improving patient health.