Cytokeratin 15 Antibody / CK15 Antibody

Cytokeratin 15 Antibody Overview

Cytokeratin 15 Antibody reagents target keratin 15 (KRT15), a type I intermediate filament protein expressed in the basal layer of stratified epithelia, particularly in skin and hair follicles. KRT15 is enriched in epithelial stem cell populations within the bulge region of hair follicles, where it helps maintain structural integrity and supports stem cell niche function.

Because of its restricted distribution, KRT15 serves as a reliable marker of basal epithelial cells and stem cell compartments. Altered expression of KRT15 has been observed in basal cell carcinomas, cervical epithelium, and inflamed skin. The Cytokeratin 15 Antibody is therefore a valuable reagent in stem cell biology, dermatology, and oncology. The CK15 Antibody also supports translational medicine by enabling precise identification of basal epithelial and stem cell lineages.

Why Choose Cytokeratin 15 Antibodies from NSJ Bioreagents?

NSJ Bioreagents provides Cytokeratin 15 Antibodies validated for immunohistochemistry, immunofluorescence, western blotting, and ELISA. Each Cytokeratin 15 Antibody undergoes strict validation for specificity and reproducibility, ensuring reliable results in complex tissue contexts.

By selecting Cytokeratin 15 Antibodies from NSJ Bioreagents, researchers gain reagents optimized for accuracy and clarity. Our antibodies deliver consistent staining in basal epithelia, reproducible protein detection in lysates, and robust performance across experimental applications. Detailed datasheets, suggested controls, and validated protocols ensure reproducibility in both research and diagnostic workflows.

Applications of Cytokeratin 15 Antibodies

The Cytokeratin 15 Antibody supports diverse applications in stem cell biology, dermatology, and oncology.

1) Stem Cell and Developmental Biology

• Cytokeratin 15 Antibodies highlight epithelial stem cell niches in hair follicles.

• The Cytokeratin 15 Antibody validates basal stem cell populations in skin biology.

• CK15 Antibody reagents support organoid research and regenerative medicine.

2) Dermatology and Skin Biology

• Cytokeratin 15 Antibodies detect expression in basal keratinocytes.

• The Cytokeratin 15 Antibody supports research into skin homeostasis and wound repair.

• CK15 Antibody reagents help distinguish basal cells from suprabasal lineages.

3) Oncology and Tumor Biology

• Cytokeratin 15 Antibodies identify basal cell carcinomas and other epithelial cancers.

• The Cytokeratin 15 Antibody supports tumor classification in pathology workflows.

• CK15 Antibody reagents validate biomarkers in cancer research.

4) Pathology and Diagnostics

• Cytokeratin 15 Antibodies confirm basal epithelial origin in biopsy panels.

• The Cytokeratin 15 Antibody provides diagnostic clarity in skin and cervical pathology.

• CK15 Antibody reagents contribute to differential diagnosis in complex epithelial cases.

5) Inflammation and Immune Responses

• Cytokeratin 15 Antibodies highlight basal epithelial remodeling during inflammation.

• The Cytokeratin 15 Antibody supports studies into skin barrier dysfunction.

6) Translational and Clinical Research

• Cytokeratin 15 Antibodies are validated in biomarker-driven oncology and dermatology studies.

• The Cytokeratin 15 Antibody supports regenerative medicine by tracking epithelial stem cells.

• CK15 Antibody reagents provide reproducibility in translational workflows.

Why Are Cytokeratin 15 Antibodies Important?

KRT15 serves as a defining marker of basal epithelial stem cells and carcinomas. The Cytokeratin 15 Antibody equips researchers with precise tools to detect and study this protein, while the CK15 Antibody broadens applications across pathology, oncology, and translational medicine.

In stem cell biology, Cytokeratin 15 Antibodies validate epithelial stem cell niches and differentiation pathways. In oncology, the Cytokeratin 15 Antibody supports classification of basal cell carcinomas and other malignancies. In pathology, CK15 Antibody reagents provide clarity in diagnosing epithelial lesions.

Clinically, accurate detection of KRT15 expression informs both dermatologic and oncologic diagnostics. Cytokeratin 15 Antibodies provide reproducibility and reliability, ensuring that laboratory insights translate into improved patient care.

Conclusion

Cytokeratin 15 is a basal epithelial and stem cell marker with critical roles in skin biology, oncology, and pathology. The Cytokeratin 15 Antibody provides validated tools for detecting KRT15 in research and diagnostics, while the CK15 Antibody supports broader translational applications. By ensuring specificity and reproducibility, these antibodies remain indispensable for advancing keratin biology and improving clinical outcomes.