Cytokeratin 7 Antibody / CK7 Antibody

Cytokeratin 7 Antibody Overview

Cytokeratin 7 Antibody reagents target keratin 7 (KRT7), a type II intermediate filament protein expressed in the simple epithelia of lung, breast, ovary, endometrium, and biliary tract. KRT7 contributes to cytoskeletal stability, cellular organization, and stress resilience. Its expression is highly tissue-specific, making it a reliable biomarker for distinguishing different epithelial lineages.

In pathology, CK7 is often paired with CK20 in immunohistochemical panels to identify the origin of carcinomas. The CK7+/CK20– profile is characteristic of lung and breast carcinomas, while CK7–/CK20+ patterns indicate colorectal cancers. Because of its diagnostic utility, the Cytokeratin 7 Antibody is widely applied in oncology and pathology. The CK7 Antibody also supports broader research in epithelial biology, developmental biology, and translational medicine.

Why Choose Cytokeratin 7 Antibodies from NSJ Bioreagents?

NSJ Bioreagents supplies Cytokeratin 7 Antibodies validated for immunohistochemistry, western blotting, immunofluorescence, ELISA, and flow cytometry. Each Cytokeratin 7 Antibody undergoes rigorous testing to ensure specificity and reproducibility across applications.

By selecting Cytokeratin 7 Antibodies from NSJ Bioreagents, researchers gain reagents optimized for consistency and clarity. Our antibodies provide robust epithelial staining in biopsies, reproducible protein detection in lysates, and dependable performance in pathology workflows. Comprehensive datasheets, recommended controls, and validated protocols support reliable results in both research and clinical settings.

Applications of Cytokeratin 7 Antibodies

The Cytokeratin 7 Antibody supports a wide variety of scientific and diagnostic applications.

1) Oncology and Tumor Classification

• Cytokeratin 7 Antibodies are widely used to classify carcinomas based on CK7/CK20 staining patterns.

• The Cytokeratin 7 Antibody helps identify primary tumors in cases of metastasis with unknown origin.

• CK7 Antibody reagents support biomarker validation in oncology.

2) Pathology and Diagnostics

• Cytokeratin 7 Antibodies confirm epithelial lineage in lung, breast, ovarian, and endometrial cancers.

• The Cytokeratin 7 Antibody supports differential diagnosis of biliary tract tumors.

• CK7 Antibody reagents provide diagnostic clarity in complex pathology cases.

3) Developmental and Stem Cell Biology

• Cytokeratin 7 Antibodies track epithelial lineage specification during embryogenesis.

• The Cytokeratin 7 Antibody validates differentiation of epithelial progenitors in vitro.

• CK7 Antibody tools support regenerative medicine and organoid development.

4) Infectious Disease and Inflammation

• Cytokeratin 7 Antibodies highlight epithelial barrier responses in respiratory and reproductive systems.

• The Cytokeratin 7 Antibody supports research into chronic inflammation affecting epithelial tissues.

5) Translational and Clinical Research

• Cytokeratin 7 Antibodies are applied in biomarker-driven clinical trials.

• The Cytokeratin 7 Antibody supports patient monitoring in precision oncology.

• CK7 Antibody reagents contribute to personalized medicine by stratifying patients based on tumor markers.

Why Are Cytokeratin 7 Antibodies Important?

KRT7 is a crucial biomarker for epithelial lineage determination and carcinoma classification. The Cytokeratin 7 Antibody equips researchers with precise tools for identifying CK7 expression, while the CK7 Antibody supports applications across oncology, pathology, and translational research.

In oncology, Cytokeratin 7 Antibodies distinguish between lung, breast, and colorectal carcinomas. In pathology, the Cytokeratin 7 Antibody confirms epithelial origin in biopsies and metastatic lesions. In developmental biology, CK7 Antibody reagents validate epithelial differentiation in stem cell and organoid models.

Clinically, CK7 remains one of the most widely used markers in diagnostic pathology. Accurate detection with Cytokeratin 7 Antibodies ensures reproducibility, reliability, and diagnostic confidence, bridging basic biology with patient care.

Conclusion

Cytokeratin 7 is a highly tissue-specific intermediate filament protein and a valuable diagnostic marker. The Cytokeratin 7 Antibody provides a validated reagent for studying KRT7 expression in oncology, pathology, and developmental biology, while the CK7 Antibody offers complementary applications across translational medicine. By ensuring specificity and reproducibility, these antibodies remain essential tools for advancing epithelial research and improving clinical diagnostics.