Cytokeratin 13 Antibody / CK13 Antibody

Cytokeratin 13 Antibody Overview

Cytokeratin 13 Antibody reagents target keratin 13 (KRT13), a type I intermediate filament protein expressed in non-keratinizing stratified squamous epithelia such as the oral mucosa, esophagus, and conjunctiva. KRT13 pairs with keratin 4, contributing to epithelial strength, barrier function, and tissue resilience.

Mutations in KRT13 are associated with white sponge nevus, a benign but chronic disorder characterized by thickened, folded oral mucosa. Altered expression of KRT13 is also observed in squamous cell carcinomas and epithelial dysplasia, where it can serve as a diagnostic marker. The Cytokeratin 13 Antibody is therefore an essential tool in oral pathology, epithelial biology, and oncology, while the CK13 Antibody further supports research in developmental biology, diagnostics, and translational medicine.

Why Choose Cytokeratin 13 Antibodies from NSJ Bioreagents?

NSJ Bioreagents provides Cytokeratin 13 Antibodies validated for immunohistochemistry, immunofluorescence, western blotting, and ELISA. Each Cytokeratin 13 Antibody is rigorously tested for specificity, reproducibility, and minimal background staining.

By selecting Cytokeratin 13 Antibodies from NSJ Bioreagents, researchers gain reagents optimized for clarity and consistency. Our antibodies provide reliable staining in oral and mucosal tissues, reproducible detection in protein lysates, and strong performance across applications. Comprehensive datasheets, suggested controls, and validated protocols support reproducibility in both basic research and clinical diagnostics.

Applications of Cytokeratin 13 Antibodies

The Cytokeratin 13 Antibody supports diverse applications in mucosal biology, pathology, and oncology.

1) Oral and Mucosal Biology

• Cytokeratin 13 Antibodies highlight KRT13 expression in non-keratinizing squamous epithelia.

• The Cytokeratin 13 Antibody supports studies of epithelial integrity in oral and esophageal tissues.

• CK13 Antibody reagents help map mucosal differentiation patterns.

2) Genetic Disorders

• Cytokeratin 13 Antibodies detect mutations responsible for white sponge nevus.

• The Cytokeratin 13 Antibody supports studies of hereditary keratinopathies.

• CK13 Antibody reagents validate biomarkers for inherited epithelial disorders.

3) Oncology and Tumor Biology

• Cytokeratin 13 Antibodies identify altered expression in squamous cell carcinomas.

• The Cytokeratin 13 Antibody supports diagnostic panels for head and neck cancers.

• CK13 Antibody reagents contribute to biomarker discovery in oral oncology.

4) Pathology and Diagnostics

• Cytokeratin 13 Antibodies confirm epithelial origin in mucosal biopsies.

• The Cytokeratin 13 Antibody helps distinguish keratinizing from non-keratinizing lesions.

• CK13 Antibody reagents enhance diagnostic accuracy in oral pathology.

5) Developmental and Stem Cell Biology

• Cytokeratin 13 Antibodies track epithelial lineage specification during embryogenesis.

• The Cytokeratin 13 Antibody validates epithelial differentiation in organoid models.

• CK13 Antibody reagents support regenerative research in mucosal tissues.

6) Translational and Clinical Research

• Cytokeratin 13 Antibodies are used in biomarker-driven oral pathology studies.

• The Cytokeratin 13 Antibody contributes to clinical diagnostics and therapeutic monitoring.

• CK13 Antibody reagents provide reproducibility in translational workflows.

Why Are Cytokeratin 13 Antibodies Important?

KRT13 is a defining marker of non-keratinizing squamous epithelia and mucosal biology. The Cytokeratin 13 Antibody equips researchers with precise tools for detecting this protein, while the CK13 Antibody broadens its applications across oncology, pathology, and translational medicine.

In oral pathology, Cytokeratin 13 Antibodies help diagnose white sponge nevus and epithelial dysplasia. In oncology, the Cytokeratin 13 Antibody supports tumor classification in squamous cell carcinomas. In developmental biology, CK13 Antibody reagents validate epithelial differentiation pathways.

Clinically, accurate detection of KRT13 informs both hereditary and acquired epithelial conditions. Cytokeratin 13 Antibodies provide reproducibility, diagnostic clarity, and translational relevance, bridging research and patient care.

Conclusion

Cytokeratin 13 is a mucosal keratin with important roles in epithelial structure, genetic disorders, and cancer. The Cytokeratin 13 Antibody provides validated tools for detecting KRT13 in oral biology, oncology, and pathology, while the CK13 Antibody offers complementary applications in diagnostics and translational medicine. By ensuring specificity and reproducibility, these antibodies remain indispensable for advancing keratin biology and improving clinical outcomes.