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Rabbit Monoclonal Antibody / Antibodies

Home >> Antibodies >> Rabbit Monoclonal Antibody / Antibodies

Rabbit Monoclonal Antibody / Antibodies

The rabbit monoclonal antibody is a relatively new addition to the research antibody portfolio of mouse/rat monoclonals, and rabbit/donkey polyclonals. Some of the advantages of a rabbit monoclonal antibody are:

  • increased sensitivity to mouse antigens
  • unlike with mouse mAbs, secondary antibody will not cross-react with mouse immunoglobulin in test samples
  • a general lower background
  • a general increase in affinity allowing for less rabbit monoclonal antibody to be used per test

    • NSJ Bioreagents expanding line of rabbit monoclonal antibodies includes:

    Found all antibodies, displaying 2591 to 2600
    His Tag Antibody (clone 6HIS/13239R)
    Catalog No : V6055
    Applications : WB
    Reactivity : All species
    Format : Purified
    Recrabbitmono
    Western blot analysis of 6xHis Tag Antibody in recombinant protein samples. Multiple epitope-tagged recombinant proteins containing V5, FLAG, HA, and His sequences were resolved by SDS-PAGE under reducing conditions and probed with 6xHis Tag Antibody clone 6HIS/13239R. Distinct immunoreactive bands are observed at approximately 18 kDa and 14 kDa, corresponding to 6xHis-tagged STAR and 6xHis-tagged tryptase proteins, respectively, as indicated. The selective detection of the His-tagged constructs demonstrates specific recognition of the His epitope tag by clone 6HIS/13239R without cross-reactivity to non-His epitope tags present in the samples.
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    p16INK4a Antibody / CDKN2A (clone MSVA-016R)
    Catalog No : V6059
    Applications : IHC
    Reactivity : Human
    Format : Purified
    Recrabbitmono
    p16 INK4a Antibody for IHC Tissue Microarray (TMA). Immunohistochemistry analysis of Cyclin-dependent kinase inhibitor 2A CDKN2A, also known as p16 INK4a, in formalin-fixed paraffin-embedded human normal and cancer tissue microarrays using recombinant rabbit monoclonal p16 INK4a antibody clone MSVA-016R. Tissue microarray (TMA) staining with HRP-DAB brown chromogen demonstrates predominantly nuclear localization with accompanying cytoplasmic staining in tumor cells across multiple carcinoma types, consistent with overexpression in settings of RB pathway dysregulation, while most normal tissues show low or focal signal. Within tumor tissue microarrays, strong and diffuse labeling is observed in several malignancies, including squamous cell carcinomas and other high-grade tumors. Evaluation across large TMA panels enables direct comparison of CDKN2A expression across diverse tissue types under standardized conditions. The observed staining patterns align with reported CDKN2A expression profiles in publicly available datasets including the Human Protein Atlas.
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    Chromogranin A Antibody / CHGA (clone MSVA-380R)
    Catalog No : V6063
    Applications : IHC
    Reactivity : Human
    Format : Purified
    Recrabbitmono
    CHGA Antibody for IHC Tissue Microarray (TMA). Immunohistochemistry analysis of Chromogranin A CHGA in formalin-fixed paraffin-embedded human normal and cancer tissue microarrays using recombinant rabbit monoclonal CHGA antibody clone MSVA-380R. Tissue microarray (TMA) staining with HRP-DAB brown chromogen demonstrates strong cytoplasmic granular localization in neuroendocrine cell populations, including adrenal medulla, pancreatic islets, and scattered enteroendocrine cells of the gastrointestinal tract, while most non-neuroendocrine tissues remain largely negative. Within tumor tissue microarrays, robust cytoplasmic positivity is observed in neuroendocrine neoplasms such as pheochromocytoma, small cell carcinoma, medullary thyroid carcinoma, and pancreatic neuroendocrine tumors, whereas non-neuroendocrine malignancies show minimal staining. Evaluation across large TMA panels enables direct comparison of CHGA expression across diverse tissue types under standardized conditions. The observed staining patterns align with reported CHGA expression profiles in the Human Protein Atlas, supporting its use as a neuroendocrine marker.
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    Calponin 1 Antibody / CNN1 (clone MSVA-455R)
    Catalog No : V6064
    Applications : IHC
    Reactivity : Human
    Format : Purified
    Recrabbitmono
    CNN1 Antibody Tissue Microarray (TMA) IHC. Immunohistochemistry analysis of Calponin 1 / CNN1 in FFPE human normal and cancer tissue microarrays using CNN1 Antibody for IHC clone MSVA-455R, a marker of smooth muscle tissue architecture. Tissue microarray staining with HRP-DAB brown chromogen shows strong cytoplasmic signal in smooth muscle cell populations, including vascular walls and gastrointestinal muscular layers, as well as myoepithelial cells in select glandular tissues, while most non-smooth muscle tissues display minimal staining. In cancer tissue arrays, robust positivity is observed in smooth muscle tumors such as leiomyoma and leiomyosarcoma, whereas non-mesenchymal malignancies are largely negative. Evaluation across TMA panels enables direct comparison of CNN1 expression across diverse tissue types under standardized conditions.
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    Decorin Antibody / DCN (clone MSVA-537R)
    Catalog No : V6066
    Applications : IHC
    Reactivity : Human
    Format : Purified
    Recrabbitmono
    Decorin Antibody for IHC Tissue Microarray (TMA). Immunohistochemistry analysis of Decorin DCN in formalin-fixed paraffin-embedded human normal and cancer tissue microarrays using recombinant rabbit monoclonal Decorin antibody clone MSVA-537R. Tissue microarray (TMA) staining with HRP-DAB brown chromogen demonstrates predominant localization within stromal extracellular matrix compartments, highlighting collagen-rich connective tissue surrounding glands, vessels, and muscle bundles, while epithelial and parenchymal cells remain largely negative. Within tumor tissue microarrays, variable stromal staining intensity is observed in tumor-associated connective tissue, consistent with extracellular matrix remodeling. Evaluation across large TMA panels enables direct comparison of Decorin expression across diverse tissue types under standardized conditions. The observed staining patterns align with reported DCN expression profiles in the Human Protein Atlas, supporting its use in extracellular matrix and stromal biology studies.
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    TdT Antibody / DNA nucleotidylexotransferase (clone MSVA-453R)
    Catalog No : V6067
    Applications : IHC
    Reactivity : Human
    Format : Purified
    Recrabbitmono
    TdT Antibody for IHC Tissue Microarray (TMA). Immunohistochemistry analysis of Terminal deoxynucleotidyl transferase DNTT, also known as TdT, in formalin-fixed paraffin-embedded human normal and cancer tissue microarrays using recombinant rabbit monoclonal TdT antibody clone MSVA-453R. Tissue microarray (TMA) staining with HRP-DAB brown chromogen demonstrates strong nuclear localization in immature thymocytes, while most non-lymphoid normal tissues and non-lymphoid carcinomas show minimal to no staining. Within tumor tissue microarrays, nuclear positivity is observed in lymphoblastic neoplasms, including acute lymphoblastic leukemia, supporting its role as a marker of immature lymphoid cells. Evaluation across large TMA panels enables direct comparison of DNTT expression across diverse tissue types under standardized conditions. The observed staining patterns align with reported TdT expression profiles in the Human Protein Atlas.
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    Estrogen Receptor alpha Antibody (clone MSVA-564R)
    Catalog No : V6071
    Applications : IHC
    Reactivity : Human
    Format : Purified
    Recrabbitmono
    Estrogen receptor alpha / ER alpha Antibody for IHC. Immunohistochemistry of Estrogen Receptor antibody for IHC in human tissue microarrays. FFPE human normal and cancer tissues were stained with Estrogen Receptor recombinant rabbit monoclonal antibody clone MSVA-564R. Nuclear staining is observed in hormone-responsive epithelial cells, with strong nuclear positivity in breast epithelium and endometrial glands, including proliferative and secretory endometrium. Placental trophoblastic cells also demonstrate nuclear signal. Most non-hormone-dependent tissues such as skeletal muscle, liver, kidney cortex and medulla, pancreas, thyroid gland, and colon mucosa show little to no nuclear staining. In the cancer tissue gallery, strong nuclear staining is present in subsets of breast carcinoma and endometrioid ovarian carcinoma, while ER negative tumors including colorectal adenocarcinoma, renal cell carcinoma, squamous cell carcinoma of the oral cavity, and prostate adenocarcinoma show absent nuclear labeling. The staining pattern is predominantly nuclear, consistent with Estrogen Receptor alpha localization.
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    Factor XIIIa Antibody / Coagulation factor XIII A chain (clone MSVA-813R)
    Catalog No : V6072
    Applications : IHC
    Reactivity : Human
    Format : Purified
    Recrabbitmono
    F13A1 Antibody for IHC Tissue Microarray (TMA). Immunohistochemistry analysis of Coagulation factor XIII A chain F13A1 in formalin-fixed paraffin-embedded human normal and cancer tissue microarrays using recombinant rabbit monoclonal antibody clone MSVA-813R. Tissue microarray (TMA) staining with HRP-DAB brown chromogen demonstrates predominant cytoplasmic localization in scattered stromal and histiocytic cell populations, consistent with expression in dermal dendrocytes and macrophage-lineage cells, while most epithelial compartments remain largely negative. In normal tissue microarrays, positive cells are observed in skin, lymph node, and placenta. Within tumor tissue microarrays, cytoplasmic staining is present in subsets of fibrohistiocytic and macrophage-rich tumors, whereas many epithelial malignancies demonstrate absent or minimal labeling. Evaluation across large TMA panels enables direct comparison of F13A1 expression across diverse tissue types under standardized conditions. The observed staining patterns align with reported expression profiles in the Human Protein Atlas and support its use as a marker of dermal dendrocytes and macrophage-associated cells.
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    SATB2 Antibody / Transcription factor SATB2 (clone MSVA-702R)
    Catalog No : V6075
    Applications : IHC
    Reactivity : Human
    Format : Purified
    Recrabbitmono
    SATB2 Antibody for IHC Tissue Microarray (TMA). Immunohistochemistry analysis of Special AT-rich sequence-binding protein 2 SATB2 in formalin-fixed paraffin-embedded human normal and cancer tissue microarrays using recombinant rabbit monoclonal antibody clone MSVA-702R. Tissue microarray (TMA) staining with HRP-DAB brown chromogen demonstrates predominantly nuclear localization, with strong nuclear staining observed in colorectal mucosal epithelial cells, while most other tissues show minimal to absent staining. Within tumor tissue microarrays, nuclear positivity is detected in colorectal adenocarcinoma and select tumors of colorectal origin, whereas many non-colorectal malignancies remain negative. Evaluation across large TMA panels enables direct comparison of SATB2 expression across diverse tissue types under standardized conditions. The observed staining patterns align with reported expression profiles in the Human Protein Atlas and support its use as a marker of colorectal epithelial differentiation.
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    ALPP Antibody / Alkaline phosphatase placental (clone MSVA-350R)
    Catalog No : V6078
    Applications : IHC
    Reactivity : Human
    Format : Purified
    Recrabbitmono
    ALPP Antibody for IHC Tissue Microarray (TMA). Immunohistochemistry analysis of Alkaline phosphatase placental ALPP in formalin-fixed paraffin-embedded human normal and cancer tissue microarrays using recombinant rabbit monoclonal antibody clone MSVA-350R. Tissue microarray (TMA) staining with HRP-DAB brown chromogen demonstrates strong membranous localization in placental trophoblastic cells, while most non-trophoblastic normal tissues remain largely negative. Within tumor tissue microarrays, selective positivity is observed in germ cell tumors including seminoma and embryonal carcinoma, supporting lineage-associated expression. Evaluation across large TMA panels enables direct comparison of ALPP expression across diverse tissue types under standardized conditions. The observed staining patterns align with reported expression profiles in the Human Protein Atlas and support its use as a marker of trophoblastic and germ cell differentiation.
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