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banner Search results for DUT

DUT Antibody / Deoxyuridine triphosphatase (clone 31D50)

Catalog No : FY12685
Applications : WB, ICC, IF, FACS
Reactivity : Human
Format : Liquid
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Western blot analysis of DUT expression in Ramos cell lysate using DUT antibody. Bands corresponding to the mitochondrial (~24-27 kDa) and the shorter nuclear/cytosolic (~18-21 kDa) isoforms can be detected; the ~18 kDa isoform can appear as a doublet consistent with modification- and processing-dependent mobility.
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DUT Antibody / Deoxyuridine triphosphatase

Catalog No : FY13460
Applications : WB, IHC, IF
Reactivity : Human
Format : Lyophilized
DUT Antibody Human Tonsil IHC. Immunohistochemistry staining of FFPE human tonsil using DUT antibody demonstrates prominent nuclear staining within proliferative lymphoid cell populations of the germinal center region, consistent with the expected localization of Deoxyuridine Triphosphatase (DUT). DUT is a genome integrity enzyme that regulates intracellular nucleotide pools and prevents inappropriate uracil incorporation into DNA during replication. The observed nuclear staining pattern is consistent with elevated nucleotide metabolism and DNA replication activity in actively proliferating lymphocytes and supports the utility of this antibody for studies of genome maintenance, DNA replication fidelity, and cellular proliferation pathways. HIER: heat-mediated antigen retrieval in EDTA buffer (pH 8.0).
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DUT Antibody / Deoxyuridine triphosphatase

Catalog No : R35363
Applications : WB, ELISA (peptide)
Reactivity : Human
Pred. Reactivity :Pig, Cow
Format : Antigen affinity purified
Deoxyuridine Triphosphatase Antibody HEK293 and HeLa WB. Western blot analysis of HEK293 and HeLa cell lysates using Deoxyuridine Triphosphatase Antibody demonstrates detection of a band at approximately 18 kDa, consistent with the mature nuclear isoform of DUT. Deoxyuridine Triphosphatase is a nucleotide metabolism enzyme that regulates intracellular dUTP pools and prevents inappropriate uracil incorporation into DNA, thereby supporting DNA replication fidelity and genome maintenance. DUT is known to exist as multiple isoforms, including a longer precursor form and a shorter processed nuclear form. The observed band is consistent with the mature nuclear isoform commonly detected in proliferating human cells. Western blot was performed using 0.1 ug/ml primary antibody. Predicted molecular weights: ~27 kDa (isoform 1) and ~18 kDa (isoform 2).
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DUT Antibody / Zebrafish

Catalog No : RZ1425
Applications : WB
Reactivity : Zebrafish
Format : Antigen affinity purified
Zebrafish DUT Antibody WB. Western blot analysis of DUT using anti-DUT antibody demonstrates a distinct immunoreactive band at approximately 20 kDa in zebrafish embryo lysate, consistent with the expected molecular weight of dUTP Pyrophosphatase (DUT). DUT is a nucleotide metabolism enzyme that hydrolyzes dUTP to dUMP, thereby preventing inappropriate uracil incorporation into DNA and supporting maintenance of genomic integrity during DNA replication. The observed expression in zebrafish embryo tissue is consistent with the essential role of DUT in nucleotide pool regulation, genome maintenance, and normal vertebrate development. Western blot was performed using 0.5 ug/ml primary antibody. Predicted molecular weight: ~20 kDa.
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