- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Endothelial cells are specialized epithelial cells that line the inner surface of blood and lymphatic vessels. These cells serve as a barrier between circulating blood and surrounding tissues, and play essential roles in angiogenesis, immune cell trafficking, hemostasis, and vascular homeostasis. In both basic research and clinical studies, accurately identifying these cells is crucial—and this is where a high-quality Endothelial Cell Marker Antibody becomes indispensable.
At NSJ Bioreagents, we offer a selection of rigorously validated Endothelial Cell Marker Antibody reagents to support research in vascular biology, immunology, and developmental biology.
The term Endothelial Cell Marker Antibody refers to antibodies that recognize proteins uniquely or predominantly expressed by endothelial cells. These markers are widely used to confirm endothelial identity in both cultured cells and tissue samples. Key protein targets include:
CD31 (PECAM1): A gold-standard marker for endothelial cells used to identify vasculature in tissue sections and cultures.
VEGFR2 (KDR): A receptor tyrosine kinase that mediates vascular endothelial growth factor signaling and is upregulated in angiogenic endothelium.
CD34: A transmembrane glycoprotein expressed by endothelial progenitors and certain vascular beds.
VE-cadherin (CDH5): A junctional marker that is critical for endothelial integrity and adherens junction formation.
Endoglin (CD105): A marker of activated endothelium involved in cardiovascular development and angiogenesis.
Each Endothelial Cell Marker Antibody from NSJ Bioreagents is produced to deliver high specificity and reproducibility across experimental systems.
NSJ Bioreagents provides Endothelial Cell Marker Antibody products optimized for a variety of immunodetection techniques. Whether your goal is to visualize blood vessel structure or isolate endothelial populations, our antibodies enable accurate detection and analysis.
Using an Endothelial Cell Marker Antibody in IHC allows researchers to map the vasculature in fixed tissue samples and monitor endothelial remodeling in pathological conditions such as cancer, stroke, or chronic inflammation.
For high-resolution imaging of endothelial architecture, IF with an Endothelial Cell Marker Antibody can reveal protein localization and co-expression with other vascular or immune cell markers.
Endothelial cells can be sorted or quantified using a fluorophore-conjugated Endothelial Cell Marker Antibody in flow cytometry, enabling analysis of expression dynamics, heterogeneity, and activation states.
An Endothelial Cell Marker Antibody is useful in protein lysate analysis to confirm expression changes in response to growth factors, cytokines, or pharmacological treatments.
Certain soluble endothelial markers can be detected in serum or culture media using ELISA kits that incorporate a specific Endothelial Cell Marker Antibody.
All Endothelial Cell Marker Antibody products from NSJ Bioreagents undergo stringent validation and quality control. We offer antibodies suitable for human, mouse, rat, and zebrafish models, enabling cross-species comparison in vascular development and disease research.
Our team is committed to helping you select the right Endothelial Cell Marker Antibody for your application. Whether your work involves tumor vasculature, endothelial differentiation, or vascular injury, NSJ Bioreagents provides the high-quality reagents you need to advance your research with confidence.
IHC staining of FFPE human angiosarcoma with CD31 antibody (clone PECAM1/3529, cat # V8297). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.