NSJ Bioreagents

Cytokeratin 19, also called CK19, KRT 19 and Keratin 19, is a type of protein that is commonly found in epithelial cells, which make up the lining of organs and tissues in the body. It can be identified in tissue and cells with a Cytokeratin 19 antibody. CK19 is also one of the most studied and widely used markers in cancer research, particularly in the field of diagnosing and predicting the progression of various types of cancer. One of the key reasons why Cytokeratin 19 is so important in cancer research is its ability to help identify cancer cells and distinguish them from normal cells. By detecting the presence of Cytokeratin 19 in a tissue or blood sample, researchers can pinpoint the location and extent of cancerous growth, which is crucial for determining appropriate treatment options. Moreover, Cytokeratin 19 has also been linked to the metastatic spread of cancer cells, as its expression is often associated with more aggressive forms of cancer. By studying the levels of Cytokeratin 19 in cancer patients, scientists can gain insights into the potential for cancer to spread and develop more effective treatment strategies. In addition to its diagnostic and prognostic value, Cytokeratin 19 has also been explored as a potential target for cancer therapy. Researchers are investigating ways to specifically target and inhibit the activity of Cytokeratin 19 in cancer cells, with the hope of slowing down or preventing the growth of tumors.

Cytokeratin 19 antibody is a valuable tool used in various research applications such as western blot, flow cytometry, immunofluorescence, immunohistochemistry, and ELISA. This versatile antibody plays a crucial role in the study of epithelial cells and has the potential to uncover important insights into disease mechanisms and diagnostic markers.

Western blotting is a commonly used technique that utilizes a Cytokeratin 19 antibody to detect the presence of Cytokeratin 19 protein in cell lysates. By using this method, researchers can analyze protein expression levels and investigate the protein's role in different cellular processes.

Flow cytometry is another powerful tool that relies on a Cytokeratin 19 antibody to identify and quantify Cytokeratin 19-expressing cells within a heterogeneous cell population. This technique enables researchers to characterize cell populations based on their CK19 expression levels and study the dynamics of epithelial cell biology.

Immunofluorescence and immunohistochemistry are imaging techniques that utilize a Cytokeratin 19 antibody to visualize CK19 protein expression in tissue samples. By using these methods, researchers can precisely pinpoint the localization of CK19 within cells and tissues, providing valuable spatial information for studying epithelial cell morphology and function.

ELISA (enzyme-linked immunosorbent assay) is a technique that uses a Cytokeratin 19 antibody to quantify CK19 protein levels in biological samples. This highly sensitive and specific method allows for the accurate measurement of Cytokeratin 19 concentrations, making it a valuable tool for biomarker discovery and disease diagnosis.

The use of a Cytokeratin 19 antibody in various research applications offers a comprehensive approach to studying epithelial cells and unraveling the complexities of cell biology. By leveraging the power of the Cytokeratin 19 antibody in techniques such as western blot, flow cytometry, immunofluorescence, immunohistochemistry, and ELISA, researchers can gain valuable insights into disease mechanisms and diagnostic markers.