NSJ Bioreagents

A KRT18 antibody is used to study the expression of KRT18 protein, also known as Keratin 18 and Cytokeratin 18, a key component of intermediate filaments that provide structural support and integrity to cells. This protein plays a crucial role in maintaining the overall shape and function of cells, as well as protecting them from mechanical stress and damage. Research has shown that abnormalities in this protein can lead to a variety of diseases, including liver and lung diseases, as well as certain types of cancers. Understanding the function of KRT18 can therefore provide valuable insights into the development and progression of these conditions. Furthermore, recent studies have highlighted the potential therapeutic benefits of targeting KRT18 in cancer treatment. By disrupting the function of this protein, researchers hope to develop new and innovative strategies for combating cancer and improving patient outcomes.

KRT18 is a type I intermediate filament protein that is expressed in epithelial cells. This protein plays a crucial role in maintaining the structural integrity of these cells. Researchers and scientists often use KRT18 antibody to study the expression and localization of this protein in various biological samples including western blot, flow cytometry, immunofluorescence, immunohistochemistry, and ELISA. Western blot is a widely used technique for detecting specific proteins in a sample. KRT18 antibody can be used in western blot to identify the presence of KRT18 protein in cell lysates. By running the protein samples on a gel and transferring them onto a membrane, researchers can visualize the protein bands using the KRT18 antibody. Flow cytometry is a powerful technique used to analyze and quantify cells based on their surface markers and intracellular proteins. KRT18 antibody can be used in flow cytometry to determine the expression levels of KRT18 in cell populations. This technique allows researchers to study the heterogeneity of KRT18 expression in different cell types. Immunofluorescence is a technique that utilizes fluorescently labeled antibodies to detect specific proteins in biological samples. KRT18 antibody can be used in immunofluorescence to visualize the localization and distribution of KRT18 protein in cells or tissues. This technique enables researchers to study the subcellular localization of KRT18 and its dynamics in response to various stimuli. Immunohistochemistry is a technique used to visualize specific proteins in tissue samples. KRT18 antibody can be used in immunohistochemistry to study the expression of KRT18 protein in various tissues. By staining tissue sections with the KRT18 antibody, researchers can analyze the expression patterns of KRT18 in normal and diseased tissues.

In conclusion, KRT18 antibody is a valuable tool for studying the expression and localization of KRT18 protein in cells and tissues. By utilizing techniques such as western blot, flow cytometry, immunofluorescence, immunohistochemistry, and ELISA, researchers can gain a better understanding of the role of KRT18 in various biological processes. KRT18 antibody can provide valuable insights into the function of this important protein.