KRT13 Antibody / Keratin 13 Antibody

KRT13 Antibody Overview

KRT13 Antibody detects keratin 13, a type I intermediate filament protein expressed in non-keratinizing stratified epithelia. KRT13 is found in oral mucosa, esophagus, conjunctiva, and other tissues requiring mechanical stability without full keratinization. Partnering with keratin 4, KRT13 helps maintain epithelial structure, barrier function, and resilience.

Mutations in KRT13 are associated with white sponge nevus, an autosomal dominant condition characterized by thickened white patches in the oral mucosa. Aberrant expression of KRT13 has also been observed in oral squamous cell carcinoma and other epithelial tumors. The KRT13 Antibody is therefore a crucial reagent for studying mucosal epithelial biology, inherited keratinopathies, and cancer pathology.

Because of its restricted expression and clinical associations, Keratin 13 Antibody reagents are widely used across oral biology, oncology, dermatology, and regenerative medicine.

Why Choose KRT13 Antibodies from NSJ Bioreagents?

NSJ Bioreagents provides KRT13 Antibodies validated for immunohistochemistry, immunofluorescence, western blotting, ELISA, and flow cytometry. Each KRT13 Antibody is rigorously tested for specificity to keratin 13, ensuring minimal cross-reactivity with other keratins such as KRT4 or KRT14.

By choosing a KRT13 Antibody from NSJ Bioreagents, researchers gain high-quality reagents optimized for reproducibility. Our antibodies deliver clear staining in mucosal epithelia, consistent detection in protein assays, and robust results across platforms. With comprehensive datasheets, positive control recommendations, and validated protocols, NSJ Bioreagents ensures that Keratin 13 Antibody products meet the needs of discovery research and diagnostic pathology.

Applications of KRT13 Antibodies

The KRT13 Antibody is applied broadly across mucosal biology, pathology, and translational science.

1) Oral and Mucosal Biology

• KRT13 Antibodies identify oral mucosa and esophageal epithelia.

• The KRT13 Antibody distinguishes non-keratinizing tissues from keratinized epithelium.

• Keratin 13 Antibody reagents support studies of mucosal integrity and wound healing.

2) Genetic Disorders

• Mutations in KRT13 cause white sponge nevus, making KRT13 Antibodies vital for research.

• The KRT13 Antibody detects keratin defects in patient biopsies and model systems.

• Keratin 13 Antibody reagents clarify disease mechanisms in inherited keratinopathies.

3) Oncology and Cancer Biology

• KRT13 Antibodies are used in oral squamous cell carcinoma research.

• The KRT13 Antibody helps clarify tumor origin and subtype in mucosal cancers.

• Keratin 13 Antibody products support biomarker discovery for cancer progression.

4) Dermatology and Pathology

• KRT13 Antibodies identify mucosal keratin patterns in inflammatory conditions.

• The KRT13 Antibody helps differentiate benign oral lesions from malignant transformation.

5) Development and Differentiation

• KRT13 Antibodies highlight epithelial lineage specification during embryogenesis.

• The KRT13 Antibody supports studies of mucosal differentiation pathways.

6) Regenerative Medicine

• KRT13 Antibodies validate stem cell-derived mucosal tissues.

• The KRT13 Antibody ensures correct epithelial identity in engineered constructs.

7) Translational Medicine and Drug Development

• KRT13 Antibodies support therapeutic testing for keratin-related diseases.

• The KRT13 Antibody is applied in biomarker validation during clinical studies.

• Keratin 13 Antibody reagents help evaluate therapies for oral and esophageal lesions.

Why Are KRT13 Antibodies Important?

Keratin 13 is a specialized epithelial marker with significance in mucosal biology and disease. The KRT13 Antibody provides precise detection of this protein, while Keratin 13 Antibody reagents more broadly support research in oral pathology, oncology, and regenerative medicine.

In basic biology, KRT13 Antibodies clarify mucosal epithelial differentiation and barrier function. In genetics, the KRT13 Antibody highlights mutations causing white sponge nevus. In oncology, Keratin 13 Antibody tools are valuable for cancer classification and biomarker discovery.

Clinically, KRT13 expression is a diagnostic marker in oral keratinopathies and mucosal cancers. By providing reliable detection, the KRT13 Antibody bridges molecular research with patient care, advancing precision medicine in oral and epithelial disease.

Conclusion

Keratin 13 is a mucosal epithelial keratin central to tissue integrity, genetic disease, and oncology. The KRT13 Antibody equips researchers and clinicians with a trusted tool for studying keratin 13 expression, while Keratin 13 Antibody reagents more broadly support discoveries in mucosal biology, regenerative medicine, and cancer diagnostics. By linking fundamental science with clinical applications, these antibodies remain indispensable for biomedical progress and improved patient outcomes.