Aquaporin 3 Antibody / AQP3 Antibody

Aquaporin 3 Antibody Overview

Aquaporin 3 Antibody reagents target AQP3, an aquaglyceroporin that facilitates transport of water, glycerol, and small solutes across membranes. Unlike classical aquaporins dedicated solely to water, AQP3 plays dual roles in both fluid regulation and energy metabolism. Its presence in epithelial and keratinocyte layers underscores its importance in skin hydration and barrier function, while its renal expression links it to systemic fluid homeostasis.

AQP3 is widely expressed in kidney collecting ducts, skin epidermis, respiratory tract, and gastrointestinal epithelium. It is also implicated in immune cell physiology and tumor biology. Dysregulated AQP3 expression has been associated with conditions such as chronic kidney disease, psoriasis, xeroderma, gastric cancer, and colorectal cancer. Because of these diverse roles, the Aquaporin 3 Antibody is an essential reagent for basic, translational, and clinical research. The AQP3 Antibody collection supports comparative studies across tissues and disease contexts.

Why Choose Aquaporin 3 Antibodies from NSJ Bioreagents?

NSJ Bioreagents provides Aquaporin 3 Antibodies validated for immunohistochemistry, western blotting, immunofluorescence, flow cytometry, and ELISA. Each Aquaporin 3 Antibody undergoes stringent validation to ensure specificity, reproducibility, and compatibility across diverse research workflows.

By choosing Aquaporin 3 Antibodies from NSJ Bioreagents, scientists gain reagents optimized for clarity and reliability. Our antibodies deliver strong staining in epithelial tissues, reproducible detection in lysates, and robust performance across translational pipelines. Detailed datasheets, validated controls, and optimized protocols provide reproducibility for both laboratory and clinical research.

Applications of Aquaporin 3 Antibodies

The Aquaporin 3 Antibody supports wide-ranging applications in fluid regulation, dermatology, oncology, and translational medicine.

1) Kidney and Renal Physiology

• Aquaporin 3 Antibodies detect AQP3 in renal collecting ducts.

• The Aquaporin 3 Antibody supports studies of water and glycerol reabsorption.

• AQP3 Antibody reagents validate biomarkers for renal and metabolic disease.

2) Dermatology and Skin Biology

• Aquaporin 3 Antibodies highlight roles in keratinocyte hydration and barrier integrity.

• The Aquaporin 3 Antibody supports studies of psoriasis and dry skin disorders.

• AQP3 Antibody reagents clarify roles in skin wound healing and regeneration.

3) Cancer and Tumor Biology

• Aquaporin 3 Antibodies detect dysregulated expression in gastric, colon, and breast cancers.

• The Aquaporin 3 Antibody supports studies of tumor proliferation and metastasis.

• AQP3 Antibody reagents provide translational biomarkers for oncology research.

4) Immune System and Inflammation

• Aquaporin 3 Antibodies detect expression in immune cells such as T lymphocytes.

• The Aquaporin 3 Antibody supports studies of immune cell migration and function.

• AQP3 Antibody reagents clarify immune–metabolic interactions.

5) Gastrointestinal and Respiratory Physiology

• Aquaporin 3 Antibodies highlight epithelial roles in fluid transport.

• The Aquaporin 3 Antibody supports studies of hydration in respiratory and GI tracts.

• AQP3 Antibody reagents validate epithelial biomarkers for physiology and disease.

6) Translational and Clinical Research

• Aquaporin 3 Antibodies are integrated into biomarker-driven oncology and dermatology studies.

• The Aquaporin 3 Antibody supports diagnostics in skin and kidney disorders.

• AQP3 Antibody reagents ensure reproducibility in translational pipelines.

Why Are Aquaporin 3 Antibodies Important?

AQP3 combines water and glycerol permeability, placing it at the intersection of hydration, energy metabolism, and disease. The Aquaporin 3 Antibody equips researchers with validated tools to explore its diverse physiological and pathological roles, while the AQP3 Antibody broadens applications across translational and diagnostic fields.

In renal biology, Aquaporin 3 Antibodies clarify mechanisms of fluid reabsorption and metabolic regulation. In dermatology, the Aquaporin 3 Antibody highlights roles in skin hydration and barrier function. In oncology, AQP3 Antibody reagents reveal tumor-associated dysregulation with diagnostic and therapeutic potential.

Clinically, AQP3 is emerging as a biomarker for cancer, kidney disease, and dermatological disorders. Reliable Aquaporin 3 Antibodies ensure reproducibility and confidence, bridging laboratory discoveries with translational and clinical medicine.

Conclusion

AQP3 is an aquaglyceroporin with wide-ranging roles in kidney physiology, skin biology, oncology, and immune function. The Aquaporin 3 Antibody provides validated reagents for studying water and glycerol transport, epithelial biology, and tumor progression, while the AQP3 Antibody expands these applications across translational pipelines. By ensuring specificity, reproducibility, and assay versatility, these antibodies remain indispensable for advancing biomedical research and improving clinical outcomes.