Epithelial Cell Adhesion Molecule Antibody / Antibodies

Epithelial Cell Adhesion Molecule Antibody Overview

Epithelial Cell Adhesion Molecule Antibody reagents target EpCAM, a glycoprotein located on the surface of most epithelial tissues. Also known as CD326, EpCAM functions as a calcium-independent adhesion molecule, participating in cell–cell interactions, proliferation, differentiation, and intracellular signaling. While essential for maintaining epithelial architecture, EpCAM’s dysregulation is strongly linked to tumor initiation and progression.

EpCAM is highly expressed in many human cancers, including those of the colon, breast, ovary, prostate, pancreas, and lung. Because of this widespread overexpression, EpCAM has become both a diagnostic marker and a therapeutic target. Beyond oncology, EpCAM expression is important during embryogenesis and in certain adult stem cell populations. The Epithelial Cell Adhesion Molecule Antibody is therefore a versatile reagent that supports cancer diagnostics, developmental biology, and translational research, while the EpCAM Antibody complements these tools across pathology and regenerative medicine.

Why Choose Epithelial Cell Adhesion Molecule Antibodies from NSJ Bioreagents?

NSJ Bioreagents offers Epithelial Cell Adhesion Molecule Antibodies validated for immunohistochemistry, western blotting, immunofluorescence, ELISA, and flow cytometry. Each Epithelial Cell Adhesion Molecule Antibody undergoes strict validation to confirm specificity and reduce non-specific binding.

By selecting Epithelial Cell Adhesion Molecule Antibodies from NSJ Bioreagents, researchers gain reagents optimized for clarity, reproducibility, and flexibility. Our antibodies deliver robust membrane staining patterns in epithelial tissues, reproducible detection in cell lysates, and consistent results in both discovery and clinical applications. Datasheets, suggested controls, and validated protocols further enhance confidence in experimental outcomes.

Applications of Epithelial Cell Adhesion Molecule Antibodies

The Epithelial Cell Adhesion Molecule Antibody supports diverse scientific and clinical applications.

1) Cancer Diagnostics and Pathology

• Epithelial Cell Adhesion Molecule Antibodies are widely used to identify carcinomas of epithelial origin.

• The Epithelial Cell Adhesion Molecule Antibody helps distinguish metastatic carcinoma from non-epithelial malignancies such as lymphomas.

• EpCAM Antibody reagents are integral to immunohistochemical panels for tumor classification.

2) Oncology and Biomarker Research

• Epithelial Cell Adhesion Molecule Antibodies detect overexpression associated with poor clinical outcomes.

• The Epithelial Cell Adhesion Molecule Antibody highlights molecular pathways in tumor initiation, progression, and metastasis.

• EpCAM Antibody tools support biomarker validation for prognosis and therapy monitoring.

3) Circulating Tumor Cells (CTCs) and Liquid Biopsy

• Epithelial Cell Adhesion Molecule Antibodies capture CTCs from blood samples, enabling non-invasive cancer monitoring.

• The Epithelial Cell Adhesion Molecule Antibody supports liquid biopsy platforms used in clinical oncology.

• EpCAM Antibody reagents contribute to translational research on metastatic dissemination.

4) Stem Cell and Developmental Biology

• Epithelial Cell Adhesion Molecule Antibodies track epithelial progenitors during embryonic development.

• The Epithelial Cell Adhesion Molecule Antibody validates epithelial differentiation in stem cell and organoid models.

• EpCAM Antibody tools provide insight into regenerative medicine approaches involving epithelial-derived tissues.

5) Immunology and Cell Biology

• Epithelial Cell Adhesion Molecule Antibodies are used to study epithelial barrier integrity and immune interactions.

• The Epithelial Cell Adhesion Molecule Antibody clarifies signaling pathways at epithelial interfaces.

• EpCAM Antibody reagents support cross-disciplinary research linking immunology with oncology.

6) Translational Medicine and Therapy Development

• Epithelial Cell Adhesion Molecule Antibodies validate biomarkers in clinical trials of anti-EpCAM therapies.

• The Epithelial Cell Adhesion Molecule Antibody is used to stratify patients for CAR-T therapy targeting EpCAM.

• EpCAM Antibody reagents provide essential data in precision oncology studies.

Why Are Epithelial Cell Adhesion Molecule Antibodies Important?

The ability to reliably detect EpCAM is critical for advancing both research and clinical medicine. The Epithelial Cell Adhesion Molecule Antibody ensures accurate identification of epithelial cells and their malignant counterparts, while the EpCAM Antibody complements this work across diagnostics and biomarker discovery.

In basic research, these antibodies clarify how cell adhesion contributes to epithelial structure and tissue homeostasis. In oncology, the Epithelial Cell Adhesion Molecule Antibody highlights overexpression patterns that predict aggressive disease. In clinical diagnostics, EpCAM Antibody tools support immunohistochemical confirmation of carcinoma origin, even in metastatic contexts.

Clinically, EpCAM is a key therapeutic target. Monoclonal antibodies and engineered cell therapies targeting EpCAM are under investigation, making detection tools essential for therapy development and patient monitoring. By ensuring reproducibility and precision, the Epithelial Cell Adhesion Molecule Antibody bridges basic biology with translational medicine.

Conclusion

EpCAM is a defining epithelial marker and an important player in cancer biology, stem cell research, and clinical diagnostics. The Epithelial Cell Adhesion Molecule Antibody equips scientists and clinicians with a validated reagent for studying EpCAM expression, while the EpCAM Antibody complements these tools in oncology, stem cell biology, and translational research. By providing specificity and reproducibility, these antibodies remain indispensable for advancing epithelial research and improving patient care.