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Home >> Antibodies >> CD11a Antibody / LFA-1

CD11a Antibody / LFA-1 [clone DF1524] (V2642)

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  Catalog No Formulation Size Price (USD)  
Image V2642-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V2642-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V2642SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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SDS-PAGE Analysis of Purified, BSA-Free CD11a Antibody (clone DF1524). Confirmation of Integrity and Purity of the Antibody.
SDS-PAGE Analysis of Purified, BSA-Free CD11a Antibody (clone DF1524). Confirmation of Integrity and Purity of the Antibody.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Clone Name DF1524
Purity Protein G affinity chromatography
UniProt P20701
Localization Cell surface
Applications Flow cytometry : 1-2ug/10^6 cells
Immunofluorescence : 1-2ug/ml
Functional studies (order BSA/sodium azide-free format) :
Limitations This CD11a antibody is available for research use only.
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Description

Recognizes a protein of 180 kDa, identified as CD11a (Leucocyte Workshop IV; Code 1524). CD11a complex with the beta 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This mAb potently blocks LFA-1 dependent homotypic cell aggregation.

Application Notes

Optimal dilution of the CD11a antibody should be determined by the researcher.

Immunogen

Human CD11a protein was used as the immunogen for the CD11a antibody.

Storage

Store the CD11a antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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