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Home >> Antibodies >> CD11a Antibody / LFA-1

CD11a Antibody / LFA-1 [clone CRIS-3] (V2159)

  Catalog No Formulation Size Price (USD)  
Image V2159-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V2159-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V2159SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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FACS staining of human PBMCs using CD11a antibody (CRIS-3).
SDS-PAGE Analysis of Purified, BSA-Free CD11a Antibody (clone CRIS-3). Confirmation of Integrity and Purity of the Antibody.
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Clone Name CRIS-3
Purity Protein G affinity chromatography
Buffer 1X PBS, pH 7.4
Gene ID 3683
Localization Cell surface
Applications Flow cytometry : 1-2ug/10^6 cells
Immunofluorescence : 1-2ug/ml Functional studies (order BSA/sodium azide-free format)
Limitations This CD11a antibody is available for research use only.
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Description

This antibody recognizes a protein of 180kDa, identified as CD11a. CD11a complexes with the beta 2 subunit of the integrin family, CD18, to form the cell surface heterodimer called LFA-1 or CD11a/CD18. LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses.

Application Notes

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

Immunogen

Stimulated human leukocytes were used as the immunogen for this CD11b antibody.

Storage

Store the CD11a antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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