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banner Search results for TPM1

TPM1 Antibody / Tropomyosin-1 / Alpha Tropomyosin (clone TPM1/4510)

Catalog No : V4387
Applications : IHC-P
Reactivity : Human
Format : Purified
TPM1 Antibody Human Skeletal Muscle IHC. Immunohistochemical staining of FFPE human skeletal muscle tissue using TPM1 Antibody / Muscle Contractile Protein Antibody (clone TPM1/4510) demonstrates strong cytoplasmic HRP-DAB brown staining throughout skeletal muscle fibers. The staining pattern is consistent with expression of TPM1 (Tropomyosin Alpha-1 Chain), an actin-binding protein that forms a critical component of the thin filament apparatus and regulates actin-myosin interactions during muscle contraction. Robust immunoreactivity within myofibers highlights the essential role of TPM1 in sarcomere organization, contractile function, and maintenance of skeletal muscle structure. HIER: boil tissue sections in pH 9, 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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TPM1 Antibody / Tropomyosin-1 / Zebrafish

Catalog No : RZ1416
Applications : WB, IHC
Reactivity : Zebrafish
Format : Antigen affinity purified
Zebrafish TPM1 Antibody Colon IHC. Immunohistochemical analysis of paraffin-embedded zebrafish colon tissue using Zebrafish TPM1 Antibody / Tropomyosin Alpha-1 Chain Antibody demonstrates strong HRP-DAB brown staining within the smooth muscle layers surrounding the intestinal wall. The staining pattern is consistent with expression of TPM1, an actin-binding protein that stabilizes actin filaments and regulates actin-myosin interactions required for muscle contraction. Positive immunoreactivity highlights the contractile apparatus of gastrointestinal smooth muscle and supports the essential role of TPM1 in muscle structure, force generation, and maintenance of tissue integrity. Heat-induced antigen retrieval was performed in EDTA buffer. Tissue sections were blocked with 10% goat serum and incubated with TPM1 antibody (2 ug/ml) overnight at 4°C, followed by Peroxidase Conjugated Goat Anti-rabbit IgG and DAB chromogen detection.
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