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banner Search results for GATA1A

GATA1 Antibody

Catalog No : RQ6768
Applications : WB, IHC-P, FACS, Direct ELISA
Reactivity : Human, Mouse
Format : Antigen affinity purified
GATA1 Antibody Human Testis IHC. IHC staining of FFPE human testis with GATA1 antibody demonstrated predominantly nuclear staining in spermatogenic cells, consistent with the localization of GATA1 as a zinc finger transcription factor. GATA1 regulates gene expression programs involved in hematopoietic differentiation and has also been implicated in Sertoli cell function and normal testicular development. The nuclear staining pattern reflects its role in transcriptional regulation. HIER was performed by boiling tissue sections in pH 8 EDTA buffer for 20 minutes followed by cooling prior to staining. These results support the utility of GATA1 Antibody for studies of transcriptional regulation, hematopoietic biology, reproductive biology, and developmental biology.
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GATA1 Antibody (clone ABCB-7)

Catalog No : RQ5460
Applications : WB, IHC
Reactivity : Human, Mouse
Format : Purified
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GATA1 Antibody Mouse Spleen IHC. Immunohistochemical staining of FFPE mouse spleen with GATA1 antibody demonstrated strong nuclear staining in erythroid precursor cells, consistent with the localization of GATA1 as a lineage-defining transcription factor. GATA1 is a zinc finger transcription factor that regulates genes required for erythropoiesis, hemoglobin synthesis, and terminal maturation of red blood cells while also contributing to megakaryocyte differentiation. The predominantly nuclear staining pattern reflects its role as a transcriptional regulator controlling hematopoietic gene expression. These results support the utility of GATA1 Antibody for studies of hematopoiesis, erythropoiesis, hematologic malignancies, and developmental hematology.
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GATA1 Antibody

Catalog No : RQ5726
Applications : WB, FACS, Direct ELISA
Reactivity : Human
Format : Antigen affinity purified
Flow cytometry testing of human K562 cells with GATA1 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= GATA1 antibody.
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GATA1 Antibody

Catalog No : R33371
Applications : WB, ELISA (peptide)
Reactivity : Human
Pred. Reactivity :Mouse, Rat, Dog, Cow
Format : Antigen affinity purified
GATA Binding Protein 1 Antibody Human PBMC WB. Western blot analysis of GATA1 expression was performed using anti-GATA1 antibody on human peripheral blood mononuclear cell (PBMC) lysate. A specific immunoreactive band is detected at approximately 43 kDa, consistent with the predicted molecular weight of GATA1. GATA1 is a zinc finger transcription factor that serves as a master regulator of erythropoiesis by controlling genes required for erythroid lineage commitment, hemoglobin synthesis, and red blood cell maturation. Although GATA1 expression is primarily associated with erythroid and megakaryocytic lineages, its detection in PBMC lysate reflects the presence of hematopoietic cell populations expressing this lineage-specific transcription factor. These results support the utility of GATA Binding Protein 1 Antibody for studies of hematopoiesis, erythropoiesis, hematopoietic transcriptional regulation, and blood cell differentiation.
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GATA1 Antibody / Zebrafish

Catalog No : RZ1469
Applications : WB
Reactivity : Zebrafish
Format : Antigen affinity purified
Zebrafish GATA1 Antibody WB. Western blot analysis of GATA1 expression was performed using anti-GATA1A antibody. Lane 1: zebrafish embryo tissue lysate. GATA1A is a zinc finger transcription factor that serves as a master regulator of erythropoiesis by controlling genes required for erythroid lineage commitment, hemoglobin synthesis, and red blood cell maturation. A specific immunoreactive band is detected at approximately 45 kDa, consistent with the expected molecular weight of GATA1A. The strong expression observed in zebrafish embryos reflects the critical role of GATA1A during primitive hematopoiesis and early blood development. These results demonstrate the utility of Zebrafish GATA1 Antibody for studies of hematopoiesis, erythropoiesis, developmental biology, and hematopoietic transcriptional regulation.
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