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banner Search results for DMPK

DMPK Antibody / Zebrafish

Catalog No : RZ1422
Applications : WB, IHC
Reactivity : Zebrafish
Format : Antigen affinity purified
Zebrafish DMPK Antibody Liver IHC. Immunohistochemical analysis of paraffin-embedded zebrafish liver tissue using Zebrafish DMPK Antibody / Myotonic Dystrophy Protein Kinase Antibody demonstrates widespread cytoplasmic staining throughout hepatocellular populations. DMPK is a serine/threonine protein kinase involved in cytoskeletal organization, intracellular signaling, and muscle-associated cellular regulatory pathways. The observed staining pattern is consistent with endogenous DMPK expression and supports the utility of this antibody for immunohistochemical detection of DMPK in zebrafish tissues. Heat-mediated antigen retrieval was performed in EDTA buffer. The tissue section was blocked with 10% goat serum and incubated overnight at 4°C with rabbit anti-DMPK antibody (2 ug/ml). Detection was performed using a peroxidase-conjugated goat anti-rabbit IgG secondary antibody followed by DAB chromogen development.
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DMPK Antibody / Myotonin-protein kinase

Catalog No : FY12356
Applications : WB
Reactivity : Mouse, Rat
Format : Lyophilized
DMPK Antibody Heart and Skeletal Muscle WB. Western blot analysis of DMPK using anti-DMPK antibody demonstrates a distinct immunoreactive band at approximately 69 kDa in rat heart, rat skeletal muscle, and mouse heart tissue lysates, consistent with the expected molecular weight of Dystrophia Myotonica Protein Kinase (DMPK). DMPK is a muscle signaling protein involved in regulation of muscle cell architecture, intracellular communication, and maintenance of normal skeletal and cardiac muscle function. The observed expression pattern in both cardiac and skeletal muscle tissues is consistent with the established biologic distribution of DMPK and supports the utility of this antibody for investigating muscle signaling pathways, myotonic dystrophy-associated mechanisms, and muscle physiology research. Western blot was performed using 0.5 ug/ml primary antibody. Predicted molecular weight: ~69 kDa.
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HSPB2 Antibody

Catalog No : R32240
Applications : WB
Reactivity : Human, Mouse, Rat
Format : Antigen affinity purified
HSPB2 Antibody Mouse and Rat Muscle WB. Western blot testing of rat skeletal muscle (lane 1), rat heart (lane 2), mouse C2C12 cells (lane 3), mouse skeletal muscle (lane 4), and mouse heart (lane 5) lysates using HSPB2 antibody detected a prominent band at approximately 22 kDa, consistent with the expected molecular weight of HSPB2 (~20 kDa). Strong expression in cardiac and skeletal muscle is consistent with the tissue-specific distribution of Heat Shock Protein Beta-2 and its role as an ATP-independent molecular chaperone. This HSPB2 Antibody, also called a Heat Shock Protein Beta-2 Antibody, is useful for investigating muscle biology, protein homeostasis, and cellular stress responses.
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