• Tel: 858.663.9055
  • separatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
banner Search results for DIO3A

DIO3 Antibody / Iodothyronine Deiodinase 3 / Zebrafish

Catalog No : RZ1417
Applications : IHC
Reactivity : Zebrafish
Format : Antigen affinity purified
Zebrafish DIO3 Antibody Liver IHC. Immunohistochemical analysis of paraffin-embedded zebrafish liver tissue using Zebrafish DIO3 Antibody / Iodothyronine Deiodinase 3 Antibody demonstrates widespread cytoplasmic HRP-DAB brown staining throughout hepatocyte populations. The staining pattern is consistent with expression of DIO3A, a thyroid hormone-inactivating enzyme that regulates local concentrations of triiodothyronine (T3) and thyroxine (T4) to maintain endocrine homeostasis. Positive immunoreactivity within hepatic tissue highlights the important role of DIO3A in thyroid hormone metabolism, developmental regulation, and control of tissue-specific endocrine signaling. Heat-induced antigen retrieval was performed in EDTA buffer. Tissue sections were blocked with 10% goat serum and incubated with DIO3A antibody (2 ug/ml) overnight at 4°C, followed by Peroxidase Conjugated Goat Anti-rabbit IgG and DAB chromogen detection.
›
img img