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DIO3 Antibody / Thyroxine 5-deiodinase

Catalog No : F55036
Applications : WB, IHC, IHC-P
Reactivity : Human, Rat
Format : Purified
DIO3 Antibody Placenta WB. Western blot analysis of human placental tissue lysate using DIO3 Antibody / Thyroid Hormone Metabolism Enzyme Antibody demonstrates a prominent immunoreactive band at approximately 31–37 kDa, consistent with the expected molecular weight range of DIO3 (Iodothyronine Deiodinase 3). DIO3 is the principal thyroid hormone-inactivating enzyme responsible for converting thyroxine (T4) and triiodothyronine (T3) into inactive metabolites, thereby regulating tissue-specific thyroid hormone availability. The strong signal observed in placental tissue is consistent with the important role of DIO3 in controlling fetal thyroid hormone exposure and maintaining endocrine homeostasis during development. Predicted molecular weight: ~34 kDa. Observed molecular weight: 31–37 kDa.
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