Hepatocyte Antibody / Hepatocyte Antibodies

Hepatocyte Antibody Overview

Hepatocyte Antibody reagents are designed to target proteins expressed in hepatocytes, the main functional cells of the liver. Hepatocytes comprise nearly 80% of the liver’s cellular mass and carry out essential processes including glucose metabolism, protein synthesis, lipid storage, and detoxification. These cells also secrete bile, regulate cholesterol levels, and maintain systemic homeostasis.

Because of their unique biology, hepatocytes express markers that are widely used in research and diagnostics. These include albumin, hepatocyte paraffin 1 (HepPar-1), cytokeratins 8/18, carbamoyl phosphate synthetase 1 (CPS1), and hepatocyte nuclear factors (HNFs). The Hepatocyte Antibody allows scientists to detect and study these markers in tissue sections, cell models, and disease samples. Meanwhile, Hepatocyte Antibodies more broadly support the investigation of liver biology, toxicology, infection, and oncology.

Why Choose Hepatocyte Antibodies from NSJ Bioreagents?

NSJ Bioreagents offers Hepatocyte Antibodies validated across immunohistochemistry, immunofluorescence, western blotting, ELISA, and flow cytometry. Each Hepatocyte Antibody undergoes strict validation to ensure specificity for hepatocyte proteins and minimal cross-reactivity with non-hepatic tissues.

By selecting Hepatocyte Antibodies from NSJ Bioreagents, scientists gain confidence in reproducibility and clarity. Our antibodies produce strong, clear staining in liver tissue, reliable protein detection in lysates, and consistent results across different applications. Detailed datasheets, recommended positive controls, and validated usage protocols further support robust and interpretable outcomes.

Applications of Hepatocyte Antibodies

The Hepatocyte Antibody is widely applied in liver research, clinical pathology, and translational medicine.

1) Liver Biology

• Hepatocyte Antibodies highlight proteins specific to hepatocytes, such as albumin and HNF4α.

• The Hepatocyte Antibody supports studies of hepatocyte differentiation and metabolic function.

• Hepatocyte Antibodies clarify pathways of detoxification, protein synthesis, and bile secretion.

2) Toxicology and Drug Safety

• Hepatocyte Antibodies are applied in toxicology studies to monitor hepatocyte health.

• The Hepatocyte Antibody validates hepatocyte identity in primary cultures and organoids.

• Hepatocyte Antibodies support drug safety assessment by tracking hepatotoxicity.

3) Pathology and Diagnostics

• Hepatocyte Antibodies distinguish hepatocellular carcinoma from metastatic tumors.

• The Hepatocyte Antibody validates hepatocyte lineage in biopsy samples.

• Hepatocyte Antibodies provide clarity in diagnostic panels for liver disease.

4) Oncology and Tumor Biology

• Hepatocyte Antibodies identify hepatocyte-derived cancers.

• The Hepatocyte Antibody supports research into hepatocellular carcinoma progression.

• Hepatocyte Antibodies are used in biomarker discovery for prognosis and therapy development.

5) Infectious Disease

• Hepatocyte Antibodies help study host–pathogen interactions in viral hepatitis.

• The Hepatocyte Antibody is applied to liver sections from patients with HBV or HCV infection.

• Hepatocyte Antibodies support translational research on liver-targeted antivirals.

6) Regenerative Medicine

• Hepatocyte Antibodies validate differentiation of stem cells into hepatocyte-like cells.

• The Hepatocyte Antibody ensures correct lineage specification in tissue engineering.

• Hepatocyte Antibodies are applied in regenerative therapy development for liver disease.

7) Translational Medicine and Clinical Trials

• Hepatocyte Antibodies are used in biomarker validation for hepatology clinical trials.

• The Hepatocyte Antibody supports patient stratification in regenerative and oncology studies.

Why Are Hepatocyte Antibodies Important?

Hepatocytes are essential for life-sustaining processes, and their dysfunction underlies many diseases. The Hepatocyte Antibody provides a precise tool for detecting hepatocyte-specific proteins, while Hepatocyte Antibodies more broadly support biomedical progress in hepatology, oncology, toxicology, and infectious disease research.

In basic science, Hepatocyte Antibodies clarify hepatocyte differentiation, metabolic function, and regeneration. In toxicology, the Hepatocyte Antibody supports studies of drug-induced liver injury. In oncology, Hepatocyte Antibodies provide tools to distinguish hepatocellular carcinoma from other malignancies.

Clinically, hepatocyte markers are integral to diagnostic pathology, biomarker discovery, and patient care in liver disease. By enabling accurate and reproducible detection, the Hepatocyte Antibody bridges basic science with clinical application, ensuring that discoveries translate into healthcare improvements.

Conclusion

Hepatocytes are vital cells that maintain systemic balance and liver function. The Hepatocyte Antibody equips scientists and clinicians with a trusted reagent for studying hepatocyte-specific proteins, while Hepatocyte Antibodies more broadly support research in liver biology, toxicology, oncology, and regenerative medicine. By connecting molecular biology with clinical relevance, these antibodies remain indispensable for advancing liver research and improving patient outcomes.