Cytokeratin 3 Antibody / CK3 Antibody

Cytokeratin 3 Antibody Overview

Cytokeratin 3 Antibody reagents target keratin 3 (KRT3), a type II intermediate filament protein expressed in the corneal epithelium. Partnering with keratin 12, KRT3 provides mechanical stability, protects against stress, and maintains transparency in the cornea. Because of its highly specific expression pattern, KRT3 serves as a reliable marker for corneal epithelial differentiation.

Mutations in KRT3 are associated with Meesmann corneal dystrophy, a hereditary disorder characterized by epithelial fragility and recurrent corneal erosions. KRT3 is also used in pathology to confirm corneal origin in ocular tissues. The Cytokeratin 3 Antibody is therefore a key reagent for corneal biology and ocular pathology, while the CK3 Antibody extends applications into regenerative ophthalmology and translational medicine.

Why Choose Cytokeratin 3 Antibodies from NSJ Bioreagents?

NSJ Bioreagents supplies Cytokeratin 3 Antibodies validated for immunohistochemistry, immunofluorescence, western blotting, and ELISA. Each Cytokeratin 3 Antibody undergoes rigorous validation to ensure specificity and reproducibility in ocular research.

By selecting Cytokeratin 3 Antibodies from NSJ Bioreagents, researchers gain reagents optimized for clarity and reliability. Our antibodies provide strong staining in corneal epithelia, consistent detection in protein lysates, and robust performance across platforms. Comprehensive datasheets, suggested controls, and validated protocols further support reproducible outcomes.

Applications of Cytokeratin 3 Antibodies

The Cytokeratin 3 Antibody supports specialized but highly impactful applications in eye research and clinical diagnostics.

1) Corneal Biology and Ocular Research

• Cytokeratin 3 Antibodies detect KRT3 in corneal epithelial cells.

• The Cytokeratin 3 Antibody clarifies epithelial differentiation in the eye.

• CK3 Antibody reagents highlight roles in corneal homeostasis and transparency.

2) Genetic Eye Disorders

• Cytokeratin 3 Antibodies identify mutations linked to Meesmann corneal dystrophy.

• The Cytokeratin 3 Antibody supports research into mechanisms of corneal fragility.

• CK3 Antibody reagents validate biomarkers for hereditary epithelial disorders.

3) Pathology and Diagnostics

• Cytokeratin 3 Antibodies confirm corneal origin in ocular biopsies.

• The Cytokeratin 3 Antibody distinguishes corneal epithelia from conjunctival or other ocular tissues.

• CK3 Antibody reagents support pathology workflows in ophthalmology.

4) Regenerative and Stem Cell Biology

• Cytokeratin 3 Antibodies track corneal epithelial differentiation in stem cell-derived organoids.

• The Cytokeratin 3 Antibody validates corneal epithelial identity in regenerative models.

• CK3 Antibody reagents support translational ophthalmology studies.

5) Inflammation and Infectious Disease

• Cytokeratin 3 Antibodies highlight corneal epithelial responses to injury or infection.

• The Cytokeratin 3 Antibody supports research into microbial keratitis and ocular inflammation.

6) Translational and Clinical Research

• Cytokeratin 3 Antibodies are validated in biomarker-driven ocular studies.

• The Cytokeratin 3 Antibody supports clinical research into corneal repair therapies.

• CK3 Antibody reagents contribute to precision medicine in ophthalmology.

Why Are Cytokeratin 3 Antibodies Important?

KRT3 is essential for corneal epithelial integrity and clarity. The Cytokeratin 3 Antibody enables researchers to detect and study KRT3 with precision, while the CK3 Antibody broadens applications in diagnostics and translational research.

In basic corneal biology, Cytokeratin 3 Antibodies highlight epithelial differentiation and tissue maintenance. In genetic eye disorders, the Cytokeratin 3 Antibody identifies pathogenic mutations. In pathology, CK3 Antibody reagents confirm corneal tissue origin and support diagnostic clarity.

Clinically, KRT3 serves as a marker for ocular diagnostics and regenerative therapies. Cytokeratin 3 Antibodies ensure reproducibility and reliability, bridging laboratory discoveries with clinical ophthalmology.

Conclusion

Cytokeratin 3 is a defining corneal epithelial marker with crucial roles in ocular health and disease. The Cytokeratin 3 Antibody equips researchers and clinicians with validated reagents for studying KRT3 in corneal biology and pathology, while the CK3 Antibody supports applications in regenerative ophthalmology and translational medicine. By ensuring specificity and reproducibility, these antibodies remain indispensable for advancing eye research and improving patient outcomes.