Aquaporin 11 Antibody / Intracellular Endoplasmic Reticulum Protein Antibody

Aquaporin 11 Antibody Overview

Aquaporin 11 (AQP11) is an atypical member of the aquaporin family that differs significantly from classical water channel proteins due to its intracellular localization and specialized cellular functions. Unlike most aquaporins that are embedded in the plasma membrane, AQP11 is primarily associated with intracellular compartments, particularly the endoplasmic reticulum (ER), where it is thought to contribute to organelle homeostasis and protein processing. Aquaporin 11 antibody reagents are widely used to study intracellular transport mechanisms, ER function, and renal physiology.

Aquaporin 11 antibody, also referred to as AQP11 antibody or intracellular aquaporin antibody, is commonly used to detect expression in kidney tissues, where AQP11 is highly expressed in proximal tubular cells. Its intracellular localization produces distinct cytoplasmic staining patterns rather than the membranous staining typically observed with other aquaporins. This makes Aquaporin 11 antibody particularly useful for distinguishing intracellular transport pathways and organelle-associated protein expression.

AQP11 has been implicated in maintaining endoplasmic reticulum integrity and cellular homeostasis. Disruption of AQP11 function has been associated with renal abnormalities and defects in tubular structure, highlighting its importance in kidney biology. Aquaporin 11 antibody enables investigation of these processes by allowing visualization of protein distribution within intracellular compartments.

In addition to its role in renal physiology, AQP11 is thought to participate in cellular stress responses and protein folding pathways linked to ER function. Aquaporin 11 antibody supports studies examining intracellular protein regulation, organelle dynamics, and mechanisms of cellular adaptation to stress.

Due to its unique localization and function, AQP11 represents a distinct subgroup within the aquaporin family. Aquaporin 11 antibody provides a valuable tool for researchers investigating intracellular water transport, ER-associated processes, and kidney-specific protein function.

👉 For a full selection of AQP11 antibody products and formats, visit our AQP11 antibody page.

Aquaporin 11 Antibody in Intracellular Biology

AQP11 is localized to intracellular compartments, particularly the endoplasmic reticulum, making it a key marker for organelle-associated processes.

Aquaporin 11 Antibody in Kidney Function

High expression in renal proximal tubules supports its role in maintaining tubular structure and intracellular homeostasis.

Aquaporin 11 Antibody in ER-Related Processes

Aquaporin 11 is linked to endoplasmic reticulum function, including protein processing and cellular stress responses.

A selection of AQP11 antibody products is shown below to support a range of research applications.

This Aquaporin 11 antibody page is part of a broader Aquaporin antibody panel offered by NSJ Bioreagents.