AQP2 Antibody / Aquaporin 2

The AQP2 antibody can be used to characterize the expression of the AQP2 protein. AQP2 (Aquaporin-2) is a key player in regulating water reabsorption in the kidney, making it a critical target for research in conditions such as diabetes insipidus and kidney disorders. AQP2 is a water channel protein that plays a crucial role in the reabsorption of water in the kidney, particularly in response to hormonal signals such as vasopressin. Dysregulation of AQP2 can lead to disorders such as nephrogenic diabetes insipidus, where the kidneys are unable to concentrate urine properly. Studying AQP2 expression and localization can provide valuable insights into these conditions and potential treatment options.

Western blotting is a common technique used to detect and quantify proteins in a sample. An AQP2 antibody can be used to specifically target and visualize AQP2 protein bands in western blot analysis, allowing researchers to assess changes in protein expression under different experimental conditions.

Immunohistochemistry and immunofluorescence are techniques used to visualize protein expression and localization in tissue samples. AQP2 antibody can be used to stain AQP2 protein in kidney tissue sections, providing valuable information on its distribution within the kidney. Immunofluorescence allows for the visualization of AQP2 in specific cell types or subcellular compartments, further enhancing our understanding of its function.

Flow cytometry is a powerful tool for analyzing and sorting individual cells based on their protein expression. Researchers can use an AQP2 antibody in flow cytometry to quantify AQP2 levels in specific cell populations, providing insights into AQP2 regulation and function at the cellular level.

AQP2 is a critical protein involved in water reabsorption in the kidney, making it an important target for research in kidney disorders. Using an AQP2 antibody in assays such as western blot, immunohistochemistry, immunofluorescence, and flow cytometry can provide valuable insights into AQP2 expression, localization, and function. By harnessing the power of the AQP2 antibody, researchers can unravel the mysteries of AQP2 and pave the way for future advancements in kidney disease research.