TL1A Antibody / TNF Superfamily Cytokine Antibody [clone rVEGI/1283] (V3637)

TL1A Antibody Protein Microarray Specificity Analysis. Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using recombinant rabbit monoclonal clone rVEGI/1283 identified TNFSF15 as the dominant target with a Z-score of 112.47 and an S-score of 90.74, supporting exceptionally strong target specificity for TL1A / TNFSF15 relative to unrelated proteins present on the array. The markedly elevated S-score demonstrates highly preferential binding to TNFSF15 with minimal off-target reactivity. The Z-score represents signal intensity generated by antibody binding relative to the mean signal across the array, while the S-score reflects the difference in signal strength between successive ranked targets and serves as a measure of relative target specificity.

TL1A Antibody Spleen IHC. Immunohistochemistry staining of FFPE human spleen tissue using recombinant monoclonal clone rVEGI/1283 demonstrates membranous and cytoplasmic HRP-DAB brown staining predominantly within vascular endothelial structures and scattered stromal-associated cells, consistent with expression of TL1A / TNFSF15 in vascular and immune-regulatory tissue compartments. The observed staining pattern aligns with the established role of this TNF superfamily cytokine in inflammatory signaling, endothelial biology, and immune pathway regulation. Heat-induced epitope retrieval was performed by boiling sections in 10 mM Tris with 1 mM EDTA, pH 9, for 10-20 min followed by cooling at room temperature for 20 min prior to staining.

SDS-PAGE analysis of purified, BSA-free TL1A antibody (clone rVEGI/1283) as confirmation of integrity and purity.