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JAG1 Antibody / Jagged 1

Catalog No : R36227
Applications : IHC, ELISA (peptide)
Reactivity : Human
Pred. Reactivity :Mouse, Rat, Dog, Pig, Cow
Format : Antigen affinity purified
Jagged 1 Antibody Kidney IHC. Immunohistochemistry staining of FFPE human kidney tissue using Jagged 1 Antibody / Notch Signaling Ligand Antibody demonstrates distinct cytoplasmic and membranous HRP-DAB brown staining within renal tubular epithelial cells. The staining pattern is consistent with expression of JAG1, a transmembrane Notch ligand that mediates cell-cell communication and regulates cellular differentiation, tissue maintenance, and developmental signaling pathways. Jagged 1 plays important roles in kidney development, epithelial homeostasis, and Notch pathway activation within renal tissues. HIER was performed by steaming tissue sections in pH 6 citrate buffer prior to immunostaining. The antibody was applied at 2 ug/ml and staining was visualized using an HRP detection system.
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