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GADD45A Antibody / GADD45AA / Zebrafish

Catalog No : RZ1355
Applications : WB
Reactivity : Zebrafish
Format : Antigen affinity purified
Zebrafish GADD45A / GADD45AA Antibody Stress Response WB. Western blot analysis of zebrafish head tissue, whole female zebrafish, and whole male zebrafish lysates using Zebrafish GADD45A Antibody demonstrates a prominent immunoreactive band at approximately 15-17 kDa, consistent with the predicted molecular weight of Growth Arrest and DNA Damage Inducible Alpha A (GADD45AA). GADD45AA is a stress-responsive protein involved in DNA damage signaling, cell cycle regulation, genomic stability, and cellular responses to environmental stress. The observed expression pattern across multiple zebrafish tissue sources is consistent with the established role of GADD45 family proteins in maintaining cellular homeostasis and coordinating protective responses to physiological and genotoxic challenges. Minor higher molecular weight immunoreactive bands are also observed and may represent cross-reactive species or other antibody-reactive proteins. Electrophoresis was performed on a 12% SDS-PAGE gel under reducing conditions followed by transfer to a nitrocellulose membrane. Signal was detected using an HRP-conjugated secondary antibody and enhanced chemiluminescent substrate.
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