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banner Search results for DCP2

DCP2 Antibody / Decapping Protein 2/ m7GpppN-mRNA hydrolase (clone PCRP-DCP2-1D6)

Catalog No : V9621
Applications : FACS, IF
Reactivity : Human
Format : Purified
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DCP2 Antibody Human MCF-7 IF. Immunofluorescent staining of PFA-fixed human MCF-7 cells with DCP2 Antibody (clone PCRP-DCP2-1D6) demonstrated punctate cytoplasmic staining (green), consistent with the localization of DCP2 (Decapping Protein 2) within cytoplasmic processing bodies (P-bodies). DCP2 is the catalytic component of the mRNA decapping complex that initiates 5'-to-3' mRNA degradation and plays a central role in RNA turnover and post-transcriptional regulation of gene expression. Phalloidin (red) labels the actin cytoskeleton, providing structural context for the intracellular distribution of DCP2, while the punctate staining pattern is characteristic of RNA processing granules involved in mRNA storage, decay, and translational control. These results support the utility of DCP2 Antibody for studies of RNA metabolism, transcript stability, processing body biology, and post-transcriptional gene regulation.
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DCP2 Antibody / Zebrafish

Catalog No : RZ1464
Applications : WB, IHC
Reactivity : Zebrafish
Format : Antigen affinity purified
Zebrafish DCP2 Antibody Spinal Cord IHC. Immunohistochemical analysis of DCP2 expression was performed using anti-DCP2 antibody in paraffin-embedded zebrafish spinal cord tissue. DCP2, also known as mRNA Decapping Enzyme 2, is the catalytic component of the mRNA decapping complex that initiates 5′-to-3′ mRNA degradation and regulates post-transcriptional gene expression. Cytoplasmic staining is observed throughout spinal cord cells, consistent with the localization of DCP2 within cytoplasmic processing bodies (P-bodies) where mRNA turnover and RNA quality control occur. The staining pattern supports the essential role of DCP2 in regulating transcript stability during neural development and maintaining cellular RNA homeostasis. These results support the utility of Zebrafish DCP2 Antibody for studies of RNA metabolism, post-transcriptional gene regulation, and vertebrate development. Heat-mediated antigen retrieval was performed in EDTA buffer, followed by incubation with DCP2 antibody at 2 ug/ml overnight at 4°C. Detection was achieved using a peroxidase-conjugated goat anti-rabbit IgG secondary antibody and DAB chromogen.
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