Blood Group Antigen A Antibody / ABO Antibody

Blood Group Antigen A Antibody Overview

Blood Group Antigen A Antibody reagents target the A antigen, one of the two primary carbohydrate modifications that define the ABO blood group system. The A antigen is formed when α-1,3-N-acetylgalactosaminyltransferase modifies the precursor H antigen by adding N-acetylgalactosamine residues. This biochemical process distinguishes individuals with type A or AB blood from those with type B, which express galactose instead, and type O, which retain the unmodified H antigen.

The ABO system is the most clinically significant in transfusion medicine. Accurate detection of the A antigen ensures compatibility in blood transfusions, organ transplants, and stem cell therapies. Beyond transfusion biology, ABO antigens influence susceptibility to infectious diseases, thrombosis risk, and even cancer progression. Because of its broad biological and clinical significance, the Blood Group Antigen A Antibody is a vital tool in hematology, immunology, and diagnostics. The ABO Antibody portfolio supports broader applications across all ABO blood group antigens.

Why Choose Blood Group Antigen A Antibodies from NSJ Bioreagents?

NSJ Bioreagents provides Blood Group Antigen A Antibodies validated for immunohistochemistry, western blotting, immunofluorescence, flow cytometry, and ELISA. Each Blood Group Antigen A Antibody undergoes rigorous validation to ensure specificity, reproducibility, and compatibility with clinical and research applications.

By selecting Blood Group Antigen A Antibodies from NSJ Bioreagents, researchers gain reagents optimized for clarity and reliability. Our antibodies deliver strong antigen detection in red blood cell preparations, reproducible staining in tissue sections, and robust performance across translational workflows. Comprehensive datasheets, validated controls, and optimized protocols further support reproducibility.

Applications of Blood Group Antigen A Antibodies

The Blood Group Antigen A Antibody supports diverse applications across hematology, transfusion medicine, and immunology.

1) Transfusion Medicine

• Blood Group Antigen A Antibodies confirm expression of the A antigen on red blood cells.

• The Blood Group Antigen A Antibody supports ABO typing and compatibility testing.

• ABO Antibody reagents complement transfusion workflows.

2) Hematology and Immunohematology

• Blood Group Antigen A Antibodies clarify biosynthesis of ABO blood group antigens.

• The Blood Group Antigen A Antibody supports glycosyltransferase research.

• ABO Antibody reagents provide context for immunohematology studies.

3) Transplantation Biology

• Blood Group Antigen A Antibodies ensure compatibility in solid organ and stem cell transplants.

• The Blood Group Antigen A Antibody supports cross-matching and donor–recipient testing.

• ABO Antibody reagents validate compatibility panels in transplantation studies.

4) Infectious Disease and Epidemiology

• Blood Group Antigen A Antibodies clarify associations between ABO blood type and pathogen susceptibility.

• The Blood Group Antigen A Antibody supports studies of malaria, norovirus, and viral infections.

• ABO Antibody reagents extend applications to epidemiological research.

5) Developmental and Stem Cell Biology

• Blood Group Antigen A Antibodies detect antigen expression during hematopoietic development.

• The Blood Group Antigen A Antibody supports stem cell differentiation and regenerative medicine.

• ABO Antibody reagents expand these studies into translational pipelines.

6) Translational and Clinical Research

• Blood Group Antigen A Antibodies are applied in biomarker-driven transfusion studies.

• The Blood Group Antigen A Antibody supports clinical workflows for precision diagnostics.

• ABO Antibody reagents ensure reproducibility across translational research.

Why Are Blood Group Antigen A Antibodies Important?

The A antigen is a cornerstone of the ABO system, governing compatibility in transfusion and transplantation. The Blood Group Antigen A Antibody provides validated reagents for antigen detection, compatibility testing, and biosynthetic studies, while the ABO Antibody provides broader support across all ABO antigens.

In hematology, Blood Group Antigen A Antibodies clarify antigen biosynthesis and expression. In transfusion medicine, the Blood Group Antigen A Antibody ensures patient safety through compatibility validation. In infectious disease research, ABO Antibody reagents reveal links between blood type and disease susceptibility.

Clinically, accurate detection of A antigen remains essential for safe transfusion practices and transplantation outcomes. Reliable antibodies guarantee reproducibility and confidence in diagnostics and research.

Conclusion

The A antigen defines one of the major ABO blood group types and plays a critical role in transfusion medicine and immunohematology. The Blood Group Antigen A Antibody provides researchers and clinicians with validated reagents for studying antigen expression, compatibility, and biosynthesis, while the ABO Antibody supports broader applications across diagnostics and translational medicine. By ensuring specificity and reproducibility, these antibodies remain indispensable for advancing blood group biology and improving patient safety.