Aquaporin 8 Antibody / AQP8 Antibody

Aquaporin 8 Antibody Overview

Aquaporin 8 Antibody reagents target AQP8, a member of the aquaporin water channel family that facilitates rapid water transport and contributes to cellular osmotic regulation. Unlike some aquaporins with highly specialized expression patterns, AQP8 is found in multiple tissues including liver, kidney, testis, pancreas, and colon. Its roles extend beyond water balance, as it is also implicated in ammonia transport and mitochondrial physiology.

AQP8 expression in hepatocytes supports bile formation and metabolic regulation, while in renal tubules it contributes to fluid reabsorption. Within mitochondria, AQP8 may help regulate hydrogen peroxide transport, linking it to oxidative stress responses. Because of these diverse functions, the Aquaporin 8 Antibody is a valuable tool for studying metabolism, mitochondrial biology, and systemic fluid balance. The AQP8 Antibody expands these studies by providing complementary reagents for cross-tissue comparisons.

Why Choose Aquaporin 8 Antibodies from NSJ Bioreagents?

NSJ Bioreagents provides Aquaporin 8 Antibodies validated for immunohistochemistry, western blotting, immunofluorescence, ELISA, and flow cytometry. Each Aquaporin 8 Antibody undergoes rigorous quality control to ensure specificity, reproducibility, and compatibility with multiple assay platforms.

By choosing Aquaporin 8 Antibodies from NSJ Bioreagents, scientists gain reagents optimized for clarity and consistency. Our antibodies deliver strong staining in liver, kidney, and intestinal tissues, reproducible protein detection in lysates, and robust performance across discovery and translational workflows. Detailed datasheets, validated controls, and optimized protocols ensure reproducibility across experimental pipelines.

Applications of Aquaporin 8 Antibodies

The Aquaporin 8 Antibody supports diverse applications across metabolism, nephrology, and mitochondrial biology.

1) Liver Physiology and Metabolism

• Aquaporin 8 Antibodies detect expression in hepatocytes and bile ducts.

• The Aquaporin 8 Antibody supports studies of bile secretion and ammonia transport.

• AQP8 Antibody reagents clarify links to liver metabolism and detoxification.

2) Kidney and Renal Research

• Aquaporin 8 Antibodies highlight roles in renal tubule water transport.

• The Aquaporin 8 Antibody supports studies of fluid reabsorption and acid–base balance.

• AQP8 Antibody reagents validate biomarkers in nephrology research.

3) Mitochondrial Biology

• Aquaporin 8 Antibodies detect mitochondrial localization in multiple tissues.

• The Aquaporin 8 Antibody supports research into hydrogen peroxide and ROS transport.

• AQP8 Antibody reagents clarify autophagy, apoptosis, and oxidative stress pathways.

4) Reproductive Biology

• Aquaporin 8 Antibodies detect expression in testis and sperm.

• The Aquaporin 8 Antibody supports studies of fertility and reproductive physiology.

• AQP8 Antibody reagents clarify water and solute regulation in gametes.

5) Gastrointestinal and Pancreatic Research

• Aquaporin 8 Antibodies identify roles in intestinal fluid absorption.

• The Aquaporin 8 Antibody supports studies of pancreatic secretion.

• AQP8 Antibody reagents extend applications to metabolic and digestive physiology.

6) Translational and Clinical Research

• Aquaporin 8 Antibodies are integrated into biomarker-driven metabolic and renal studies.

• The Aquaporin 8 Antibody supports diagnostics for liver and kidney disease.

• AQP8 Antibody reagents provide reproducibility across translational pipelines.

Why Are Aquaporin 8 Antibodies Important?

AQP8 regulates water balance across multiple organ systems and contributes to unique processes such as ammonia and hydrogen peroxide transport. The Aquaporin 8 Antibody equips researchers with validated tools for studying its physiological and pathological roles, while the AQP8 Antibody supports translational and comparative applications.

In liver research, Aquaporin 8 Antibodies highlight roles in bile formation and detoxification. In renal biology, they clarify contributions to fluid reabsorption. In mitochondrial physiology, the Aquaporin 8 Antibody provides tools for exploring oxidative stress and apoptosis.

Clinically, AQP8 is emerging as a biomarker for metabolic disease, renal dysfunction, and oxidative stress–related pathologies. Reliable Aquaporin 8 Antibodies ensure reproducibility and confidence, linking laboratory insights with clinical applications.

Conclusion

AQP8 is a multifunctional aquaporin that regulates water, ammonia, and hydrogen peroxide transport across diverse tissues. The Aquaporin 8 Antibody provides validated reagents for studies in liver, kidney, mitochondria, and reproductive biology, while the AQP8 Antibody expands applications across translational medicine. By ensuring specificity, reproducibility, and assay versatility, these antibodies remain indispensable for advancing aquaporin research and improving clinical outcomes.