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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Aquaporin 5 (AQP5) is a membrane water channel protein that plays a key role in regulating fluid secretion in exocrine glands and epithelial tissues. It facilitates transmembrane water movement in response to osmotic gradients, contributing to the production of saliva, tears, and pulmonary fluids. Aquaporin 5 antibody reagents are widely used to study epithelial physiology, glandular secretion, and fluid transport mechanisms.
Aquaporin 5 antibody, also referred to as AQP5 antibody or epithelial water channel antibody, is commonly used to detect expression in salivary glands, lacrimal glands, and lung epithelium. In these tissues, AQP5 is localized to the apical membrane of secretory epithelial cells, where it supports fluid secretion into ducts and luminal spaces. This distinct localization produces characteristic staining patterns that make Aquaporin 5 antibody a useful marker for glandular epithelial function.
AQP5 plays a critical role in maintaining hydration of mucosal surfaces and supporting normal glandular activity. Aquaporin 5 antibody enables investigation of these processes by allowing visualization of protein expression in secretory tissues. Its function in fluid transport is essential for proper physiological function in respiratory and digestive systems.
In addition to its role in normal physiology, AQP5 expression has been studied in conditions such as dry eye disease, salivary gland dysfunction, and pulmonary disorders where fluid secretion is altered. Aquaporin 5 antibody is therefore used in research focused on epithelial dysfunction and glandular pathology. Changes in AQP5 expression may also be associated with tumor progression in certain epithelial cancers.
Aquaporin 5 antibody supports research into epithelial transport, glandular secretion, and tissue hydration, providing a valuable tool for studying fluid regulation in specialized tissues.
👉 For a full selection of AQP5 antibody products and formats, visit our AQP5 antibody page.
AQP5 is highly expressed in salivary and lacrimal glands, where it regulates fluid secretion and supports glandular function.
Aquaporin 5 antibody enables analysis of water transport across epithelial membranes in lung and glandular tissues.
Altered AQP5 expression is associated with disorders affecting fluid secretion, making it relevant for studies of epithelial dysfunction.
A selection of AQP5 antibody products is shown below to support a range of research applications.
IHC staining of FFPE rat lung with Aquaporin 5 antibody (cat # RQ4537) at 1ug/ml. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.