Aquaporin 1 Antibody / AQP1 Antibody

Aquaporin 1 Antibody Overview

Aquaporin 1 Antibody reagents target AQP1, the first identified aquaporin and one of the most widely studied water channels. AQP1 facilitates rapid, selective transport of water across cell membranes while excluding ions and solutes. This channel is essential for maintaining fluid balance and osmotic gradients across numerous tissues.

AQP1 is highly expressed in kidney proximal tubules and descending thin limbs of Henle’s loop, where it enables efficient water reabsorption. It is also present in red blood cells, vascular endothelia, eye, and choroid plexus, where it contributes to cerebrospinal fluid secretion. Dysregulated expression or mutations in AQP1 have been linked to impaired water balance, pulmonary hypertension, and other pathological states. Because of its broad physiological relevance, the Aquaporin 1 Antibody is a cornerstone tool for nephrology, vascular biology, and translational research. The AQP1 Antibody complements these applications with validated reagents for diverse workflows.

Why Choose Aquaporin 1 Antibodies from NSJ Bioreagents?

NSJ Bioreagents provides Aquaporin 1 Antibodies validated for immunohistochemistry, western blotting, immunofluorescence, flow cytometry, and ELISA. Each Aquaporin 1 Antibody undergoes rigorous testing to ensure specificity, reproducibility, and compatibility across multiple assay platforms.

By choosing Aquaporin 1 Antibodies from NSJ Bioreagents, scientists gain reagents optimized for clarity and consistency. Our antibodies provide strong staining in renal, vascular, and brain tissues, reproducible detection in protein lysates, and dependable performance across translational research. Detailed datasheets, validated controls, and optimized protocols ensure reproducibility in both laboratory and clinical pipelines.

Applications of Aquaporin 1 Antibodies

The Aquaporin 1 Antibody supports wide-ranging applications across nephrology, vascular research, and clinical biology.

1) Kidney and Renal Physiology

• Aquaporin 1 Antibodies detect expression in proximal tubules and Henle’s loop.

• The Aquaporin 1 Antibody supports studies of renal water reabsorption.

• AQP1 Antibody reagents validate biomarkers for water balance disorders.

2) Blood and Red Cell Biology

• Aquaporin 1 Antibodies detect expression in erythrocyte membranes.

• The Aquaporin 1 Antibody supports studies of red cell hydration and gas transport.

• AQP1 Antibody reagents provide biomarkers for blood-related physiology.

3) Vascular and Endothelial Research

• Aquaporin 1 Antibodies highlight expression in capillary endothelia.

• The Aquaporin 1 Antibody supports studies of pulmonary hypertension.

• AQP1 Antibody reagents clarify roles in angiogenesis and vascular biology.

4) Eye and Cerebrospinal Fluid Secretion

• Aquaporin 1 Antibodies detect expression in ocular tissues and choroid plexus.

• The Aquaporin 1 Antibody supports studies of cerebrospinal fluid dynamics.

• AQP1 Antibody reagents extend research into eye physiology and glaucoma.

5) Oncology and Tumor Biology

• Aquaporin 1 Antibodies highlight dysregulated expression in tumor angiogenesis.

• The Aquaporin 1 Antibody supports studies of metastasis and tumor vascularization.

• AQP1 Antibody reagents validate biomarkers for oncology research.

6) Translational and Clinical Research

• Aquaporin 1 Antibodies are integrated into biomarker-driven renal and vascular studies.

• The Aquaporin 1 Antibody supports diagnostics for pulmonary and renal disease.

• AQP1 Antibody reagents ensure reproducibility in translational pipelines.

Why Are Aquaporin 1 Antibodies Important?

AQP1 is a classical water channel with widespread expression and vital physiological roles. The Aquaporin 1 Antibody equips researchers with validated reagents for studying water transport, vascular biology, and disease pathology, while the AQP1 Antibody expands applications across translational medicine.

In nephrology, Aquaporin 1 Antibodies clarify mechanisms of renal water reabsorption. In vascular biology, the Aquaporin 1 Antibody highlights endothelial functions and roles in pulmonary hypertension. In oncology, AQP1 Antibody reagents uncover angiogenic mechanisms in tumor biology.

Clinically, AQP1 serves as both a biomarker and a therapeutic target, making reliable detection critical for research and diagnostics. Reliable Aquaporin 1 Antibodies ensure reproducibility, bridging basic biology with translational and clinical applications.

Conclusion

AQP1 is a foundational aquaporin, essential for water transport in kidney, blood, brain, and vascular systems. The Aquaporin 1 Antibody provides validated reagents for studying renal physiology, endothelial biology, cerebrospinal fluid regulation, and tumor angiogenesis, while the AQP1 Antibody extends applications across translational pipelines. By ensuring specificity, reproducibility, and assay versatility, these antibodies remain indispensable for advancing aquaporin research and improving clinical outcomes.