Aquaporin 1 Antibody / Endothelial Water Channel Protein Antibody

Aquaporin 1 Antibody Overview

Aquaporin 1 (AQP1), also known as aquaporin-1 or CHIP28, is a membrane-integrated water channel protein that facilitates rapid transmembrane water transport and is widely expressed in endothelial cells and fluid-transporting epithelia. Aquaporin 1 antibody reagents are commonly used to study vascular biology, fluid homeostasis, and membrane permeability, where AQP1 plays a central role in regulating water movement across cell membranes.

Aquaporin 1 antibody, also referred to as AQP1 antibody or CHIP28 antibody, is highly useful for detecting endothelial and epithelial expression patterns in tissues such as kidney, lung, and microvasculature. The protein is strongly expressed in capillary endothelial cells, renal proximal tubules, and certain epithelial cell types, reflecting its function in fluid exchange and filtration processes. Its membrane localization produces distinct staining patterns consistent with its role as a water channel protein.

AQP1 is an important marker of vascular endothelium and is frequently used in studies examining angiogenesis, vascular permeability, and tissue fluid balance. Aquaporin 1 antibody enables investigation of endothelial cell distribution and function, particularly in contexts where fluid transport and microvascular dynamics are altered. Its expression in capillary networks makes it a valuable marker for identifying vascular structures in both normal and pathological tissues.

In addition to its physiological roles, Aquaporin 1 has been implicated in tumor biology, where its expression may contribute to tumor angiogenesis and microenvironment regulation. Aquaporin 1 antibody is therefore used in cancer research to evaluate vascular density, endothelial involvement, and fluid dynamics within tumor tissues. Changes in AQP1 expression have also been associated with edema, inflammation, and tissue remodeling.

Aquaporin 1 antibody supports research focused on membrane transport, vascular function, and epithelial physiology, providing a reliable tool for detecting this widely expressed water channel protein across biological systems.

👉 For a full selection of AQP1 antibody products and formats, visit our AQP1 antibody page.

Aquaporin 1 Antibody in Endothelial Biology

AQP1 is highly expressed in endothelial cells, where it regulates water permeability and supports microvascular function, making it a key marker of vascular structures.

Aquaporin 1 Antibody in Fluid Transport Systems

Expression of AQP1 in kidney and lung tissues highlights its role in fluid exchange, filtration, and maintenance of tissue hydration.

Aquaporin 1 Antibody in Tumor Angiogenesis

AQP1 expression in tumor-associated vasculature supports its use in studies of angiogenesis, vascular remodeling, and tumor microenvironment dynamics.

A selection of AQP1 antibody products is shown below to support a range of research applications.

This Aquaporin 1 antibody page is part of a broader Aquaporin antibody panel offered by NSJ Bioreagents.