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Home >> Antibodies >> CD70 Antibody

CD70 Antibody [clone BU69] (V3033)

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  Catalog No Formulation Size Price (USD)  
Image V3033-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V3033-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V3033SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name BU69
Purity Protein G affinity chromatography
UniProt P32970
Localization Cell surface
Applications ELISA (order BSA/sodium azide-free format for coating) :
Inhibits T cell proliferation induced by dendritic cells (order BSA/sodium azide-free format) :
Flow cytometry : 1-2ug/10^6 cells
Immunofluorescence : 1-2ug/ml
Immunoprecipitation : 1-2ug/500ug protein lysate
Immunohistochemistry (Frozen) : 0.5-1ug/ml for 30 min at RT
Limitations This CD70 antibody is available for research use only.
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Description

CD70 belongs to the tumor necrosis factor (TNF) ligand family. It is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.

Application Notes

Optimal dilution of the CD70 antibody should be determined by the researcher.

1. This mAb blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells.

Immunogen

The human WM-1 (Waldenstrom s macroglobulinemia) cell line was used as the immunogen for the CD70 antibody.

Storage

Store the CD70 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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