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Home >> Antibodies >> TLR7 Antibody

TLR7 Antibody [clone 3F11-2C9-D8] (F54019)

  Catalog No Formulation Size Price (USD)  
Image F54019-0.1ML In PBS with 50% glycerol and 0.03% ProClin 300 0.1 ml 399
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Western blot testing of A) CHO-K1 cells transfected with a partial TLR7 protein and B) untransfected CHO-K1 cell lysate using TLR7 antibody at 1:2000. Expected size of the partial protein ~40 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1
Clone Name 3F11-2C9-D8
Purity Protein G affinity
UniProt Q9NYK1
Applications Western blot : 1:1000
Limitations This TLR7 antibody is available for research use only.
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Description

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. [UniProt]

Application Notes

The stated application concentrations are suggested starting points. Titration of the TLR7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A human recombinant partial protein was used as the immunogen for this TLR7 antibody.

Storage

Store the TLR7 antibody at -20oC.

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