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Home >> Antibodies >> SOX2 Antibody

SOX2 Antibody (F47909)

  Catalog No Formulation Size Price (USD)  
Image F47909-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F47909-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of SOX2 antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SOX2 gene (2).
SOX2 antibody flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt P48431
Localization Cytoplasmic, nuclear
Applications Western blot : 1:1000
Flow Cytometry : 1:10-1:50
Limitations This SOX2 antibody is available for research use only.
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Description

SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.

Application Notes

Titration of the SOX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This SOX2 antibody was produced from rabbits immunized with a recombinant protein of human SOX2.

Storage

Aliquot the SOX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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