- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
SIRT6 Antibody (F49522)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
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F49522-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 429 | |
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F49522-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 199 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Purified |
| UniProt | Q8N6T7 |
| Applications | IHC (Paraffin) : 1:50-1:100 Western Blot : 1:1000 |
| Limitations | This SIRT6 antibody is available for research use only. |
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SIRT6 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
Titration of the SIRT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 290-319 from the human protein was used as the immunogen for this SIRT6 antibody.
Aliquot the SIRT6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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