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Home >> Antibodies >> SIRT3 Antibody

SIRT3 Antibody (F49519)

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  Catalog No Formulation Size Price (USD)  
Image F49519-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 439
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F49519-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 205
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SIRT3 Antibody WB. Western blot analysis of lysate from (1) 293 and (2) HepG2 cell line using SIRT3 antibody at 1:1000. Predicted size: 44/28 kDa (full/processed)
SIRT3 Antibody HEK293 Cell WB. SIRT3 antibody western blot analysis in 293 cell lysate. Predicted size: 44/28 kDa (full/processed)
SIRT3 Antibody HepG2 Cell WB. SIRT3 antibody western blot analysis in HepG2 lysate. Predicted size: 44/28 kDa (full/processed)
SIRT3 Antibody Breast Cancer IHC. Immunohistochemistry analysis of FFPE human breast carcinoma tissue stained with the SIRT3 antibody.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Antigen affinity purified
Host Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q9NTG7
Applications Western Blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Limitations This SIRT3 antibody is available for research use only.
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Description

SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The SIRT3 is included in class I of the sirtuin family.

Researchers studying mitochondrial metabolism, oxidative stress adaptation, and cellular energy regulation pathways may also be interested in our SIRT3 Antibody / Mitochondrial Metabolism Regulator page featuring validated immunofluorescence, flow cytometry, and protein microarray specificity data for mitochondrial biology research.

Application Notes

Titration of the SIRT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 250-279 from the human protein was used as the immunogen for this SIRT3 antibody.

Storage

Aliquot the SIRT3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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