- Tel: 858.663.9055
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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Alpha 2-antiplasmin (or a2-antiplasmin or plasmin inhibitor) is a serine protease inhibitor (serpin) responsible for inactivating plasmin. Plasmin is an important enzyme that participates in fibrinolysis and degradation of various other proteins. This protein is encoded by the SERPINF2 gene. This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
Optimal dilution of the SERPINF2 antibody should be determined by the researcher.
Recombinant human protein (amino acids K461-K491) was used as the immunogen for the SERPINF2 antibody.
After reconstitution, the SERPINF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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