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Home >> Antibodies >> SERPINA3 Antibody

SERPINA3 Antibody (R31341)

  Catalog No Formulation Size Price (USD)  
Image R31341 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 389
Western blot testing of SERPINA3 antibody and SMMC-7721 cell lysate. Predicted molecular weight: 47/65kDa (unmodified/glycosylated).
IHC-P: SERPINA3 antibody testing of human liver cancer tissue
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt P01011
Applications Western blot : 0.5-1ug/ml
IHC (FFPE) : 0.5-1ug/ml
Limitations This SERPINA3 antibody is available for research use only.
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Description

Alpha 1-antichymotrypsin, also called serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 or GIG24, is an alpha globulin glycoprotein that is a member of the serpin superfamily. In humans, it is encoded by the SERPINA3 gene. This gene is mapped to 14q32.13. The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimers disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the SERPINA3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the middle region of human SERPINA3 (EMPFDPQDTHQSRFY) was used as the immunogen for this SERPINA3 antibody.

Storage

After reconstitution, the SERPINA3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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