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- Tel: 858.663.9055
- Email: info@nsjbio.com
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The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
Titration of the S100A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 45-75 from the human protein was used as the immunogen for this S100A1 antibody.
Aliquot the S100A1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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