- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
ROR alpha Antibody / RORA (F54563)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54563-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
|
F54563-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity purified |
| UniProt | P35398 |
| Localization | Nuclear |
| Applications | Immunofluorescence : 1:25 Western blot : 1:500-1:2000 Flow cytometry : 1:25 (1x10e6 cells) |
| Limitations | This ROR alpha antibody is available for research use only. |
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RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene.
The stated application concentrations are suggested starting points. Titration of the ROR alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 193-222 from the human protein was used as the immunogen for the ROR alpha antibody.
Aliquot the ROR alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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