- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Mammaglobin A Antibody Recombinant Mouse MAb / SCGB2A2 Antibody [clone rMGB/6619] (V9143)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
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V9143-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 559 | |
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V9143-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 259 | |
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V9143SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Mouse |
| Clonality | Recombinant Mouse Monoclonal |
| Isotype | Mouse IgG1, kappa |
| Clone Name | rMGB/6619 |
| Purity | Protein A/G affinity |
| UniProt | Q13296 |
| Localization | Cytoplasm |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml |
| Limitations | This Mammaglobin A antibody is available for research use only. |
|
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Mammaglobin A (SCGB2A2) is a secreted epithelial glycoprotein encoded by the SCGB2A2 gene and belongs to the secretoglobin family of small secreted proteins associated with mammary epithelial differentiation. Mammaglobin A Antibody Recombinant Mouse MAb rMGB/6619 recognizes Mammaglobin A / SCGB2A2 and targets a protein widely studied as a marker of mammary epithelial cells and breast carcinoma.
Mammaglobin A antibody, also referred to as Mammaglobin antibody or SCGB2A2 antibody in the literature, detects a protein predominantly produced by luminal epithelial cells of the mammary gland. Mammaglobin A is secreted into glandular lumens as part of normal epithelial secretory activity within mammary tissue. Because of this relatively restricted tissue distribution, Mammaglobin A expression has been extensively examined in studies of mammary gland biology and breast tumor origin.
Structurally, Mammaglobin A contains conserved cysteine residues characteristic of secretoglobin family proteins, contributing to stable folding and function within epithelial secretory pathways. As a secreted epithelial protein, Mammaglobin is typically detected in the cytoplasm of mammary epithelial cells and may also be present within luminal secretions depending on tissue architecture and experimental preparation. These localization patterns reflect the role of Mammaglobin within glandular epithelial secretory processes.
Expression of Mammaglobin A is frequently observed in breast epithelial cells and breast carcinoma specimens, where it reflects the differentiated state of mammary epithelial tumor cells. In breast tumors, Mammaglobin expression is often detected within epithelial tumor cell populations forming glandular structures, while surrounding stromal cells and non-epithelial tissue components typically show little to no staining. These expression patterns have made Mammaglobin a widely studied marker in breast cancer research and epithelial tumor characterization.
Mammaglobin A Antibody Recombinant Mouse MAb (clone rMGB/6619) is developed as a recombinant mouse monoclonal antibody designed to detect Mammaglobin A / SCGB2A2 in protein expression studies. Antibodies targeting Mammaglobin are commonly used in investigations of mammary epithelial differentiation, tumor biology, and protein localization in breast tissue and breast cancer models.
Optimal dilution of the Mammaglobin A Antibody Recombinant Mouse MAb should be determined by the researcher.
Recombinant full-length human Mammaglobin/SCGB2A2 protein was used as the immunogen for the recombinant Mammaglobin A antibody.
Aliquot the Mammaglobin A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Mammaglobin antibody, SCGB2A2 antibody, Mammaglobin breast marker antibody, Secretoglobin family 2A member 2 antibody, Mammary gland secretoglobin antibody
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