IRF4 Antibody RM352 / Interferon Regulatory Factor 4 Monoclonal Antibody [clone RM352] (R20374)

IRF4 Antibody RM352 Staining in Human Tonsil by IHC. Immunohistochemistry staining of FFPE human tonsil tissue with IRF4 Antibody (clone RM352) at 1:800 shows strong brown nuclear labeling in a distinct population of lymphoid cells. Positive nuclei are particularly evident outside and around the lighter germinal-center region, while many surrounding lymphocytes remain unstained. The discrete nuclear localization is consistent with the function of IRF4 as an immune regulatory transcription factor. This staining pattern demonstrates detection of IRF4 in human lymphoid tissue using this Interferon Regulatory Factor 4 Monoclonal Antibody.

IRF4 Antibody RM352 Staining in Human Appendix by IHC. Immunohistochemistry staining of FFPE human appendix tissue with IRF4 Antibody (clone RM352) at 1:800 shows prominent brown nuclear labeling in scattered immune cells distributed throughout the lymphoid-rich tissue surrounding the intestinal glands. Positive cells are readily distinguished from the numerous hematoxylin-counterstained negative nuclei, producing a discrete nuclear staining pattern consistent with IRF4 localization. The selective labeling demonstrates detection of IRF4-expressing immune cells in human appendix using this Interferon Regulatory Factor 4 Monoclonal Antibody.

IRF4 Antibody RM352 Staining in Human Melanoma by IHC. Immunohistochemistry staining of FFPE human melanoma tissue with IRF4 Antibody (clone RM352) at 1:250 shows strong brown nuclear labeling in a distinct subset of cells within the tissue. The positive nuclei are sharply defined against a larger population of weakly stained or negative cells, supporting nuclear localization of the transcription factor rather than diffuse cytoplasmic reactivity. This heterogeneous nuclear staining demonstrates detection of IRF4 in human melanoma tissue using this Interferon Regulatory Factor 4 Monoclonal Antibody.

IRF4 Antibody RM352 Detection in Human Raji B Cells by WB. Western blot testing of human Raji B-cell lysate with IRF4 Antibody (clone RM352) at a 1:2000 dilution shows a strong, discrete band migrating at approximately 50-51 kDa. This closely matches the predicted molecular weight of approximately 51 kDa for human IRF4, with little additional reactivity visible on the blot. The well-defined signal demonstrates detection of the MUM1/IRF4 protein in human Raji B cells using this Interferon Regulatory Factor 4 Monoclonal Antibody.