- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Recombinant Chromogranin A antibody is a reliable reagent for detecting chromogranin A, a secretory protein encoded by the CHGA gene and expressed in neuroendocrine cells. Chromogranin A resides in dense-core secretory granules, where it contributes to the packaging, storage, and release of peptide hormones and neuropeptides. Because of its wide expression in endocrine tissues and tumors, chromogranin A is extensively studied in endocrinology, neuroscience, and oncology.
Chromogranin A undergoes proteolytic cleavage to yield biologically active peptides such as vasostatin, pancreastatin, and catestatin. These fragments regulate cardiovascular activity, glucose metabolism, and neuronal signaling, illustrating the diverse functions of this protein. Elevated chromogranin A levels in plasma serve as a biomarker for neuroendocrine tumors, pheochromocytomas, and paragangliomas, making it clinically significant.
The Recombinant Chromogranin A antibody clone rCHGA/798 ensures reproducible and specific detection of this protein. Recombinant production eliminates batch-to-batch variability, providing consistent performance in sensitive applications. Clone rCHGA/798 has been employed in neuroendocrine research, cancer diagnostics, and hormone regulation studies. It has been cited in peer-reviewed publications exploring neuroendocrine tumor classification and hormone processing pathways, confirming its value in both basic and clinical research.
Research using clone rCHGA/798 has clarified how chromogranin A participates in granule biogenesis, peptide processing, and secretion. Its detection continues to support translational work where chromogranin A is used as a diagnostic marker and as a tool for monitoring therapeutic response. This antibody also aids in mapping neuroendocrine differentiation in tumors of uncertain origin, providing insight into disease classification.
NSJ Bioreagents supplies this Recombinant Chromogranin A antibody to support research in neuroendocrine biology, hormone regulation, and oncology. The protein is also known as CHGA antibody, secretory granule protein antibody, parathyroid secretory protein 1 antibody, and neuroendocrine tumor marker antibody, reflecting the broad range of names encountered in the literature.
Optimal dilution of the recombinant Chromogranin A antibody should be determined by the researcher.
Recombinant human full-length protein was used as the immunogen for the recombinant Chromogranin A antibody.
Store the recombinant Chromogranin A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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