- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Recombinant Chromogranin A Antibody / Rabbit Monoclonal [clone CHGA/1815R] (V3825)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
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V3825-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 100 ug | 539 | |
|
|
V3825-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 20 ug | 249 | |
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V3825SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 539 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG, kappa |
| Clone Name | CHGA/1815R |
| Purity | Protein A affinity chromatography |
| UniProt | P10645 |
| Localization | Cytoplasmic |
| Applications | Immunohistochemistry (FFPE) : 0.5-1ug/ml for 30 min at RT |
| Limitations | This recombinant Chromogranin A antibody is available for research use only. |
|
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Recombinant Chromogranin A antibody provides a reliable method to study chromogranin A, a secretory granule protein encoded by the CHGA gene. Chromogranin A resides in neuroendocrine tissues such as the adrenal medulla, pituitary, and pancreas, where it regulates hormone packaging and secretion. Because of its role in neuroendocrine signaling and tumor biology, it remains a valuable target in endocrinology and oncology research.
Beyond its structural function in dense-core vesicles, chromogranin A serves as the precursor for several bioactive peptides, including pancreastatin and catestatin. These peptides regulate processes ranging from insulin secretion to cardiovascular function. Dysregulation of chromogranin A expression and processing has been implicated in metabolic disease, hypertension, and cancer, broadening its relevance beyond endocrinology.
The Recombinant Chromogranin A antibody clone CHGA/1815R delivers precise and reproducible detection. Recombinant production ensures consistent performance across experimental systems, eliminating variability between lots. Clone CHGA/1815R has been cited in peer-reviewed publications examining chromogranin A as a neuroendocrine tumor biomarker and as a regulator of secretory granule function. Its inclusion in published work highlights its importance as a dependable antibody for research and diagnostic applications.
Research using clone CHGA/1815R has provided insights into how chromogranin A levels can inform disease monitoring. Circulating chromogranin A has diagnostic utility for detecting neuroendocrine tumors and assessing tumor burden, while tissue expression patterns contribute to classification and prognosis. This antibody continues to advance understanding of neuroendocrine biology, peptide regulation, and cancer pathology.
NSJ Bioreagents supplies this Recombinant Chromogranin A antibody to facilitate research into endocrine signaling and tumor diagnostics. Chromogranin A is also referred to as CHGA antibody, neuroendocrine secretory protein antibody, dense-core granule protein antibody, and parathyroid secretory glycoprotein antibody, reflecting its diverse roles in research literature.
Optimal dilution of the recombinant Chromogranin A antibody should be determined by the researcher.
Recombinant human protein was used as the immunogen for the recombinant Chromogranin A antibody.
Store the recombinant Chromogranin A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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