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Home >> Antibodies >> Recombinant CDX2 Antibody / Caudal-type homeobox protein 2

Recombinant CDX2 Antibody / Caudal-type homeobox protein 2 [clone CDX2/9298R] (V5614)

  Catalog No Formulation Size Price (USD)  
Image V5614-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 539
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V5614-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 249
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V5614SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 539
Microvalidated Recrabbitmono
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IHC staining of FFPE human colon tissue with recombinant CDX2 antibody (clone CDX2/9298R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant CDX2 antibody (clone CDX2/9298R) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Clone Name CDX2/9298R
Purity Protein A/G affinity
UniProt Q99626
Localization Nucleus
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This recombinant CDX2 antibody is available for research use only.
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Description

The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids ?and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma.However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.

Application Notes

Optimal dilution of the recombinant CDX2 antibody should be determined by the researcher.

Immunogen

Recombinant full-length human CDX2 protein was used as the immunogen for the recombinant CDX2 antibody.

Storage

Aliquot the recombinant CDX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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