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- Tel: 858.663.9055
- Email: info@nsjbio.com
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It recognizes a protein of 90kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
Optimal dilution of the recombinant Calnexin antibody should be determined by the researcher.
A recombinant N-terminal region fragment of human Calnexin protein (within amino acids 1-300) was used as the immunogen for the recombinant Calnexin antibody.
Aliquot the recombinant Calnexin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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